scholarly journals Immunosuppression in Helminth Infection

10.5772/26537 ◽  
2012 ◽  
Author(s):  
Maria Doligalska ◽  
Katarzyna Donskow-ysoniewsk
Keyword(s):  
Helminth Infection

Malnutrition and Helminth Infection Affect Performance of an Interferon  -Release Assay

PEDIATRICS ◽  
2010 ◽  
Vol 127 (2) ◽  
pp. peds.2010-0885d-peds.2010-0885d
Keyword(s):  
Helminth Infection ◽  
Release Assay

scholarly journals Immunity to helminth infection (WS-091)

2010 ◽  
Vol 22 (Suppl_1_Pt_5) ◽  
pp. v10-v10
Keyword(s):  
Helminth Infection

Response to helminth infection of sheep selected for resistance to Haemonchus contortus

1990 ◽  
Vol 20 (8) ◽  
pp. 1015-1018 ◽  
Author(s):  
R WOOLASTON ◽  
I BARGER ◽  
L PIPER
Keyword(s):  
Haemonchus Contortus ◽  
Helminth Infection

scholarly journals The development and validation of an age-structured model for the evaluation of disease control strategies for intestinal helminths

Parasitology ◽  
1994 ◽  
Vol 109 (3) ◽  
pp. 389-396 ◽  
Author(s):  
M. S. Chan ◽  
H. L. Guyatt ◽  
D. A. P. Bundy ◽  
G. F. Medley
Keyword(s):  
Helminth Infection ◽  
Control Strategies ◽  
Intestinal Helminth ◽  
Intestinal Helminths ◽  
Parasite Control ◽  
Age Related ◽  
Control Programmes ◽  
Age Structured ◽  
Development And Validation ◽  
Age Structured Model

SummaryEpidemiological modelling can be a useful tool for the evaluation of parasite control strategies. An age-structured epidemiological model of intestinal helminth dynamics is developed. This model includes the explicit representation of changing worm distributions between hosts as a result of treatment, and estimates the morbidity due to heavy infections. The model is used to evaluate the effectiveness of different programmes of age-targeted community chemotherapy in reducing the amount of morbidity due to helminth infection. The magnitude of age-related heterogeneities is found to be very important in determining the results of age-targeted treatment programmes. The model was verified using field data from control programmes for Ascaris lumbricoides and Trichuris trichiura, and was found to provide accurate predictions of prevalence and mean intensities of infection during and following different control regimes.

scholarly journals Neither Primary nor Memory Immunity to Mycobacterium tuberculosis Infection Is Compromised in Mice with Chronic Enteric Helminth Infection

2015 ◽  
Vol 83 (3) ◽  
pp. 1217-1223 ◽  
Author(s):  
Wasiulla Rafi ◽  
Kamlesh Bhatt ◽  
William C. Gause ◽  
Padmini Salgame
Keyword(s):  
Mycobacterium Tuberculosis ◽  
T Regulatory Cells ◽  
Helminth Infection ◽  
Treg Cells ◽  
Helminth Species ◽  
Nippostrongylus Brasiliensis ◽  
T Regulatory Cell ◽  
Chronic Infections ◽  
Mycobacterium Tuberculosis Infection ◽  
Content Type

Previously we had reported thatNippostrongylus brasiliensis, a helminth with a lung migratory phase, affected host resistance againstMycobacterium tuberculosisinfection through the induction of alternatively activated (M2) macrophages. Several helminth species do not have an obligatory lung migratory phase but establish chronic infections in the host that include potent immune downregulatory effects, in part mediated through induction of a FoxP3+T regulatory cell (Treg) response. Treg cells exhibit duality in their functions in host defense againstM. tuberculosisinfection since their depletion leads to enhanced priming of T cells in the lymph nodes and attendant improved control ofM. tuberculosisinfection, while their presence in the lung granuloma protects against excessive inflammation.Heligmosomoides polygyrusis a strictly murine enteric nematode that induces a strong FoxP3 Treg response in the host. Therefore, in this study we investigated whether host immunity toM. tuberculosisinfection would be modulated in mice with chronicH. polygyrusinfection. We report that neither primary nor memory immunity conferred byMycobacterium bovisBCG vaccination was affected in mice with chronic enteric helminth infection, despite a systemic increase in FoxP3+T regulatory cells. The findings indicate that anti-M. tuberculosisimmunity is not similarly affected by all helminth species and highlight the need to consider this inequality in human coinfection studies.

scholarly journals Cutting Edge: The BTLA–HVEM Regulatory Pathway Interferes with Protective Immunity to Intestinal Helminth Infection

2015 ◽  
Vol 194 (4) ◽  
pp. 1413-1416 ◽  
Author(s):  
Minka Breloer ◽  
Wiebke Hartmann ◽  
Birte Blankenhaus ◽  
Marie-Luise Eschbach ◽  
Klaus Pfeffer ◽  
...  
Keyword(s):  
Protective Immunity ◽  
Helminth Infection ◽  
Cutting Edge ◽  
Intestinal Helminth ◽  
Regulatory Pathway

A Cost-Effectiveness Analysis of Anthelminthic Intervention for Community Control of Soil-Transmitted Helminth Infection: Levamisole and Ascaris lumbricoides

1996 ◽  
Vol 82 (4) ◽  
pp. 527 ◽  
Author(s):  
Celia V. Holland ◽  
E. O'Shea ◽  
S. O. Asaolu ◽  
O. Turley ◽  
D. W. T. Crompton
Keyword(s):  
Cost Effectiveness ◽  
Ascaris Lumbricoides ◽  
Helminth Infection ◽  
Cost Effectiveness Analysis ◽  
Community Control ◽  
Effectiveness Analysis
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