scholarly journals Tight Junctions

10.5772/35166 ◽  
2012 ◽  
Author(s):  
Lorenza Gonzalez-Mariscal ◽  
Miguel Quiros ◽  
Mnica Diaz-Coranguez ◽  
Pablo Bautist
Keyword(s):  
Tight Junctions

Freeze-etch observations on the tight junctions of sertoli cells grown in organ culture with FSH

1978 ◽  
Vol 36 (2) ◽  
pp. 340-341
Author(s):  
Rita Meyer ◽  
Zoltan Posalaky ◽  
Dennis Mcginley
Keyword(s):  
Organ Culture ◽  
Tight Junctions ◽  
Sertoli Cell ◽  
Germ Cells ◽  
Sertoli Cells ◽  
Barrier Function ◽  
Cell Junction ◽  
Intramembranous Particles ◽  
Junctional Complexes ◽  
Oriented Parallel

The Sertoli cell tight junctional complexes have been shown to be the most important structural counterpart of the physiological blood-testis barrier. In freeze etch replicas they consist of extensive rows of intramembranous particles which are not only oriented parallel to one another, but to the myoid layer as well. Thus the occluding complex has both an internal and an overall orientation. However, this overall orientation to the myoid layer does not seem to be necessary to its barrier function. The 20 day old rat has extensive parallel tight junctions which are not oriented with respect to the myoid layer, and yet they are inpenetrable by lanthanum. The mechanism(s) for the control of Sertoli cell junction development and orientation has not been established, although such factors as the presence or absence of germ cells, and/or hormones, especially FSH have been implicated.

Functional proflling of intestinal tight junctions in vitro highlights mechanistic differences between tight junction modulators+

2001 ◽  
Vol 120 (5) ◽  
pp. A701-A701
Author(s):  
C WATSON ◽  
M ROWLAND ◽  
G WARHURST
Keyword(s):  
Tight Junction ◽  
Tight Junctions
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