The Clinical Relevance of Gastroesophageal Reflux Disease and Laryngopharyngeal Reflux in Clinical Practice

Gastroesophageal reflux disease (GERD) is one of the most common pathologies in modern clinical practice. Laryngopharyngeal reflux (LPR) is considered to be an extraesophageal manifestation of GERD and is characterized by retrograde ingestion of gastric content into the larynx and pharynx, leading to recurrent otolaryngological symptoms. Classical manifestations of LPR are hoarseness, perspiration, dryness and feeling of lump in the throat, coughing. There is no «gold standard» for the diagnosis of LPR. At the same time, several instrumental methods are used in clinical practice to verify the diagnosis: laryngoscopy and EGDS are the most common, and in some cases - 24-hour pH-metry and impedancemetry. In the case of an established diagnosis of LPR, it is recommended to use a standard dosage of PPI twice a day for 3–6 months.

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Gastroesophageal reflux disease: actual aspects of diagnostics and treatment in real clinical practice of therapist

Medical Council ◽

10.21518/2079-701x-2019-14-22-31 ◽

2019 ◽

pp. 22-31

Author(s):

D. I. Trukhan ◽

I. A. Viktorova

Keyword(s):

Clinical Practice ◽

General Practitioner ◽

Gastroesophageal Reflux Disease ◽

Gastroesophageal Reflux ◽

Proton Pump ◽

Reflux Disease ◽

Point Of View ◽

Diagnosis And Treatment ◽

Multimorbid Patients ◽

Real Clinical Practice

Gastroesophageal reflux disease (GERD) in terms of prevalence ranks first among gastroenterological diseases. A large number of works on the diagnosis and treatment of GERD, forms the point of view that about GERD «everything is long and well known.» However, in real clinical practice, for various reasons, possible «pitfalls, reefs and shallows» are not taken into account, the underestimation of which can introduce certain difficulties in the diagnosis and treatment. This review discusses the most significant aspects of the diagnosis and treatment of GERD in real clinical practice by a general practitioner and general practitioner. Currently, proton pump inhibitors are the main drugs for the treatment of GERD and other acid-dependent diseases. The results of numerous foreign and Russian studies indicate the effectiveness and safety of pantoprazole in the treatment of GERD, especially in multimorbid patients due to the lower potential of drug interactions. The presence on the Russian pharmaceutical market of two forms of release of the generic drug pantoprazole Panum® increases the availability of effective and safe therapy for GERD and other acid-dependent diseases.

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Gastroesophageal Reflux Disease in Patients with Eustachian Tube Catarrh

International Journal of Phonosurgery & Laryngology ◽

10.5005/jp-journals-10023-1107 ◽

2015 ◽

Vol 5 (2) ◽

pp. 61-66 ◽

Cited By ~ 1

Author(s):

Anuja Bhargava ◽

Meenu Cherian ◽

Tambi A Cherian

Keyword(s):

Gastroesophageal Reflux Disease ◽

Gastroesophageal Reflux ◽

Eustachian Tube ◽

Proton Pump Inhibitors ◽

Proton Pump ◽

Reflux Disease ◽

Laryngopharyngeal Reflux ◽

Common Symptom ◽

Medical Sciences ◽

Middle Ear Pressure

ABSTRACT Background Eustachian tube catarrh could be due to laryngopharyngeal reflux besides other causes. Objectives To assess gastroesophageal reflux disease (GERD) in patients with Eustachian tube catarrh and the effect of proton pump inhibitors on symptoms of Eustachian tube disease. Methodology A total of 50 patients were selected with symptoms of Eustachian tube catarrh and evaluated prospectively in the ENT Outpatient Department of the Pondicherry Institute of Medical Sciences, Puducherry. Results The group consisted of 15 (30%) males and 35 (70%) females. The largest group was of the age of 45 years and above (44%). The most common symptom of Eustachian tube catarrh was itching (84%), followed by otalgia (76%) and popping sensation on swallowing (74%). On otoscopic examination, the commonest grade of tympanic membrane retraction was grade I (57%), on tympanometry 90% of cases had middle ear pressure in range −100 to +100. The middle compliance ranged from 0.5 to 1.75 (normal) in 86% of the cases. The tympanomeric curve was type A (normal) in 78% of the cases and type C in 8% of the cases. At the end of 4 and 8 weeks, the response of treatment to proton pump inhibitors was significantly higher (z = 3.53, p < 0.05) in the studied group. Conclusion Laryngopharyngeal reflux (LPR) could be an important etiological factor in Eustachian tube catarrh. The treatment, with proton pump inhibitors, of Eustachian tube catarrh with no local identifiable cause, could be very useful to this subsect of patients. How to cite this article Bhargava A, Cherian M, Cherian TA, Gupta S. Gastroesophageal Reflux Disease in Patients with Eustachian Tube Catarrh. Int J Phonosurg Laryngol 2015;5(2): 61-66.

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