scholarly journals Development and validation of RP-HPLC assay of chlorhexidine in gingival crevicular fluid

2014 ◽  
Vol 64 (2) ◽  
pp. 69-82 ◽  
Author(s):  
Liljana Bogdanovska ◽  
Sehmedin Saliu ◽  
Mirjana Popovska ◽  
Aneta Dimitrovska ◽  
Liljana Ugrinova ◽  
...  
Keyword(s):  
Gingival Crevicular Fluid ◽  
Hplc Assay ◽  
Rp Hplc ◽  
Crevicular Fluid ◽  
Development And Validation

RP-HPLC assay of doxycycline in human saliva and gingival crevicular fluid in patients with chronic periodontal disease

2013 ◽  
Vol 78-79 ◽  
pp. 170-175 ◽  
Author(s):  
Marko S. Denić ◽  
Slavica M. Sunarić ◽  
Ljiljana G. Kesić ◽  
Ivan Z. Minić ◽  
Radmila R. Obradović ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Human Saliva ◽  
Hplc Assay ◽  
Rp Hplc ◽  
Chronic Periodontal Disease ◽  
Crevicular Fluid

scholarly journals Development and validation of RP HPLC method for determination of betamethasone dipropionate in gingival crevicular fluid

2013 ◽  
Vol 63 (3) ◽  
pp. 419-426 ◽  
Author(s):  
Liljana Bogdanovska ◽  
Mirjana Popovska ◽  
Aneta Dimitrovska ◽  
Rumenka Petkovska
Keyword(s):  
Gingival Crevicular Fluid ◽  
Local Treatment ◽  
Hplc Method ◽  
Single Step ◽  
Betamethasone Dipropionate ◽  
Therapeutic Monitoring ◽  
Rp Hplc ◽  
Crevicular Fluid ◽  
Development And Validation

Abstract A simple RP HPLC method for quantification of betamethasone dipropionate (BDP) in gingival crevicular fluid (GCF) has been developed and validated. GCF represents a valuable matrix for therapeutic monitoring of drugs used in the treatment of periodontal disease. The proposed method involves single step extraction for sample preparation. The calibration curve for BDP was linear over the concentration range of 0.10-2.00 μg mL-1 (R2 = 0.9971). RSD values of intra- and inter-day precision ranged 2.2-4.5 and 1.6-5.7 %, while accuracy values were higher than 96.6 and 97.0 %, respectively. The described method can be successfully applied for determination of betamethasone concentrations in GCF obtained from patients with chronic periodontitis after local treatment with BDP cream 0.5 mg g-1.

scholarly journals DEVELOPMENT AND VALIDATION OF TELMISARTAN IN TABLET DOSAGE FORM BY RP-HPLC ASSAY TECHNOLOGY

2019 ◽  
Vol 14 (01) ◽  
pp. 125-130
Author(s):  
George Kumar Saha ◽  
Beena Kumari ◽  
Prabhat Kumar Upadhyay ◽  
Manish Kumar ◽  
Shailendra Bhatt ◽  
...  
Keyword(s):  
Dosage Form ◽  
Hplc Assay ◽  
Rp Hplc ◽  
Development And Validation ◽  
Tablet Dosage
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