Plants from Urban Parks as Valuable Cosmetic Ingredients: Green Extraction, Chemical Composition and Activity

The research on the possibilities of using biowaste from urban green areas is scarce. In this work, four plants, widely distributed in urban parks in Central Europe (Lotus corniculatus, Medicago lupulina, Knautia arvensis and Plantago major) were extracted using eco-friendly solvents based either on aqueous cyclodextrin solutions (hydroxypropyl-β-cyclodextrin or γ-cyclodextrin) or natural deep eutectic solvents based on glycerol, betaine and glucose. Metal content was determined using total reflection X-ray fluorescence (TXRF). The content of selected metabolites was determined using UV-VIS spectrophotometric methods and HPLC. Skin-related bioactivity was assessed using tyrosinase and elastase inhibition assays. The selected plants contained metals beneficial for skin health, such as zinc and calcium, while having a low content of toxic heavy metals. The extracts contained the bioactive phenolics such as quercetin, kaempferol, luteolin and apigenin. L. corniculatus was the most potent tyrosinase inhibitor, while K. arvensis showed the most pronounced elastase inhibitory activity. The employed solvents actively contributed to the observed bioactivity. The results indicate that the biowaste obtained from urban parks represents an ecologically acceptable alternative to conventional cultivation for the preparation of ecologically acceptable, high-value cosmetic products.

FUNGSI PENGAWASAN TERHADAP PEREDARAN KOSMETIK BERBAHAN TERLARANG PADA BALAI PENGAWAS OBAT DAN MAKANAN KOTA KENDARI (Studi Kasus Pasar Sentral Kota Kendari)

This study aims to determine and describe the function of controlling the circulation of prohibited cosmetics at the Food and Drug Supervisory Agency (BPOM) Kendari City (Central Market Case Study of Kendan City). conclusions/verification. The results showed that Drugs and Food (BPOM) Kendani City in terms of carrying out activities carried out according to previously established standards have been carried out properly, namely carrying out intensification or inspections to places where there are indications that there are prohibited cosmetics containing ingredients. And the aspect of carrying out monitoring is not optimal because some people who are still unfamiliar with gadgets or applications cannot use BPOM Mobile, this application can be used before buying cosmetics so that they are not only tempted by instant results but also pay attention to whether the cosmetics are safe or not. Has been carried out properly, supervision through print media and social media to educate the public about choosing cosmetic products that are safe and free of prohibited substances. In terms of taking corrective actions if they get deviations from obstacles, they are not optimal, because there are still some people who are less cooperative if they know of cosmetics containing prohibited substances.

Halal Label and Product Quality: Case Study Wardah Cosmetic Product Purchase Decision

The development of the Indonesian cosmetic industry is relatively rapid because cosmetic products have become primary needs in Indonesia which the population is predominantly Muslim. This development caused competitive competition between cosmetics brands in Indonesia. Because of this competition, Wardah cosmetics is considering the halal label in its products and the quality of the products to increase consumer purchasing decisions. This research uses quantitative, associative methods to investigate the relationship between halal brands and product quality with the purchasing decision of Wardah cosmetics, especially in Surabaya. The number of samples used is 100 Muslim respondents who used Wardah cosmetics products in Surabaya. The data analysis technique used is multiple correlation coefficient analysis using SPSS version 25. The study results showed that halal labeling and product quality simultaneously had a significant and robust relationship with the purchasing decision of Wardah cosmetic products. While partially, the halal labels and product quality had a moderate and meaningful relationship with the purchase decision of Wardah cosmetics products.

Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products

The current status of controversy regarding the use of certain preservatives in cosmetic products makes it necessary to seek new ecological alternatives that are free of adverse effects on users. In our study, the natural terpene thymoquinone was encapsulated in chitosan nanoparticles. The nanoparticles were characterized by DLS and TEM, showing a particle size of 20 nm. The chemical structure, thermal properties, and release profile of thymoquinone were evaluated and showed a successful stabilization and sustained release of terpenes. The antimicrobial properties of the nanoparticles were evaluated against typical microbial contaminants found in cosmetic products, showing high antimicrobial properties. Furthermore, natural moisturizing cream inoculated with the aforementioned microorganisms was formulated with thymoquinone-chitosan nanoparticles to evaluate the preservative efficiency, indicating its promising use as a preservative in cosmetics.

Anti-Phototoxicity Effect of Phenolic Compounds from Acetone Extract of Entada phaseoloides Leaves via Activation of COX-2 and iNOS in Human Epidermal Keratinocytes

The extract from Entada phaseoloides was employed as active ingredients of natural origin into cosmetic products, while the components analysis was barely reported. Using LC-DAD-MS/qTOF analysis, eleven compounds (1–11) were proposed or identified from acetone extract of E. phaseoloides leaves (AE). Among them, six phenolic compounds, protocatechuic acid (2), 4-hydroxybenzoic acid (3), luteolin-7-O-β-d-glucoside (5), cirsimaritin (6), dihydrokaempferol (9), and apigenin (10), were isolated by various chromatographic techniques. Protocatechuic acid (2), epicatechin (4), and kaempferol (11) at a concentration 100 μM increased the HaCaT cells viability of the UVB-irradiated cell without any cytotoxicity effect and reduced the expression of COX-2 and iNOS inflammation gene. Moreover, compounds 2 and 4 could have potent effects on cell migration during wound closure. These results suggest that compounds 2, 4, and 11 from AE have anti-photoaging properties and could be employed in pharmaceutical and cosmeceutical products.

Differentiated approach to the prescription of dexpanthenol drugs in the practice of a pediatrician

The article provides information about the features of the structure, development and differentiated approach to the appointment of dexapanthenol preparations used for the prevention and complex treatment of skin diseases in children of wounded age. Regular use of leave-on cosmetic products including body creams and lotions is very high among children aged 0–4 years. However, in most cases, recommendations for the use of topical baby skin care medicinal products and/or cosmetic products are based not on scientific evidence, but on common sense, expert opinions, advertising, personal preferences of parents, pharmacists, dermatologists and/or pediatricians. For example, adsorbing properties of baby powders are insufficient, and after absorbing moisture, they actually turn to “urine compresses” that aggravate the epidermis injury. After swelling, the starch-containing powders represent an excellent growth media for pathogenic and opportunistic microflora. It is noted that only proper skin care for young children allows you to preserve its integrity and functional state. Special attention is paid to the preparations of the Bepanten® series in the form of cream and ointment, which meet all the criteria for topical products, and can be used for the prevention and treatment of skin diseases in young children, effectively protecting the skin from irritants, promoting its healing and recovery, having an anti-inflammatory effect, increasing its elasticity, elasticity and are recommended for use as a means of basic care. Their effectiveness has been repeatedly confirmed in the numerous domestic and foreign randomized controlled studies in new-born populations at different gestational ages, which provided the scientific justification for their common use in the ‘real-life’ practice of pediatricians, dermatologists and allergists.

Licorice (Glycyrrhiza glabra, G. uralensis, and G. inflata) and Their Constituents as Active Cosmeceutical Ingredients

The interest in plant extracts and natural compounds in cosmetic formulations is growing. Natural products may significantly improve cosmetics performance since they have both cosmetic and therapeutic-like properties, known as cosmeceutical effects. Glycyrrhiza genus, belonging to the Leguminosae family, comprises more than 30 species, widely distributed worldwide. The rhizomes and roots are the most important medicinal parts currently used in pharmaceutical industries and in the production of functional foods and food supplements. In the last few years, the interest in their potential activities in cosmetic formulations has greatly increased. Glycyrrhiza spp. extracts are widely implemented in cosmetic products for their good whitening effect. The biological effects of Glycyrrhiza extracts are especially ascribable to the occurrence of specialized metabolites belonging to the flavonoid class. This review focuses on the botany and the chemistry of the main investigated Glycyrrhiza spp. (G. glabra, G. uralensis, and G. inflata) along with their cosmeceutical activities categorized as skin anti-aging, photoprotective, hair care, and anti-acne. It has been highlighted how, along with Glycyrrhiza extracts, three main flavonoids namely licochalcone A, glabridin, and dehydroglyasperin C are the most investigated compounds. It is noteworthy that other molecules from licorice show potential cosmeceutical effects. These data suggest further investigations to clarify their potential value for cosmetic industries.

Changes in consumers’ awareness and interest in cosmetic products during the pandemic

This research investigates the impact of the COVID-19 pandemic on consumers’ perspectives of beauty and individual cosmetic products. Since the first confirmed case of COVID-19 was announced on December 31st, 2019, the search volumes of Google News have been updated and information on confirmed cases of the disease has been collected. This study used Python 3.7, NodeXL 1.0.1, and Smart PLS 3.0 to analyze consumer awareness of cosmetic products during the pandemic. The results reveal that consumers’ perspectives of beauty are impacted by a pandemic. Global consumers perceive skincare as an important aspect during the pandemic, while the importance of makeup fell after the outbreak. The awareness of skincare and makeup products has changed. The spread of the pandemic (SOP) has a positive impact on skincare products, but a negative impact on makeup products, except for eye makeup products, which was positive. Finally, the SOP was not significant in terms of consumers’ interest in masks. Fifth, interest in masks showed a positive relationship with interest in skincare products, such as cleansing products, while a negative relationship was observed with interest in makeup products. Overall, this study concludes that pandemics certainly have an impact on global consumers’ perspectives. As a pandemic spread, interest in skincare products increases, while interest in makeup products decreases. This study has academic significance in that it investigates the effects of consumption of cosmetic products during the stay-at-home rules. It can be used as standard information for setting marketing strategies in pandemic-like situations in the future.

Silver-calcium-borates as better replacement for conventional organic antimicrobials in cosmetic products

Microbes generally develop resistance towards organic antibacterial agents like ampicillin, Sulfonamides, methicillin, etc., and progressively new drugs are being invented to replace them. Hence, replacement of organic antibacterial agents with inorganic analogues requires constant research and the present investigation reports alternatives for conventional antimicrobial agents like methylparaben, diazolidinyl urea, etc., in the cosmetic products with silver incorporated calcium borates. The chemically synthesized silver-calcium borates have been analyzed for phase purity using powder XRD analysis, nature of bonding using FTIR vibrations, and morphology using SEM. The antibacterial and antifungal studies were carried out for the novel inorganic silver-calcium borates incorporated cosmetic products. The products were also subjected to thermal & photostability studies and found to be comparable with that of commercially available products. A minimum quantity of 3 ppm of silver-calcium borate concentration was required to bring about nearly 100% bacterial reduction in the cosmetic products.

The Role of the Malaysian Islamic Development Corporation in Monitoring Halal Food and Cosmetic Products: A Descriptive Analysis Case

This study aims to highlight the guiding, and moral role that the Malaysian Foundation for Islamic Development presents in all aspects of Malaysian life as a complete and comprehensive method advocated by Islam as a law that draws from the Sharia and its provisions based on the prophetic saying: “The permissible is clear, and the forbidden is clear, and there are suspicious matters between them that many people are not aware of…”. It also shows that Malaysian Foundation for Halal food act rely on consuming Halal meet only, with permissibility to benefit from slaughtered animals' skin as pure material which was given to us by Allah. The study also shows the Foundation’s interest in following up the non-Muslim community’s treatment of animals, and that they should treat them with respect and care. The Foundation advocates to perform slaughtering animals as stipulated in Shariah, avoiding electric-shock of animals, or throwing them in an inhuman manner. In order to make this goal a reality on the ground, the Foundation appeals to the regulatory authorities to follow up the implementation of the standard specifications for halal products. The Malaysian foundation focuses on halal food ingredients, cosmetics products, medicines, and other Halal related products that are useful to the mankind, accompanied by ethical standards. The researcher relied on the descriptive and deductive analytical method, with the aim to reach the desired outcomes. The study includes two axes: First, it deals with the role of the Malaysian Development Foundation in supervising exports and imports of Malaysian food and medicine products. Second: it studies the situation of the (Halal) brand logo on Malaysian products assessing its profitability in international trade arena and Shariah supervisory professionalism which is adhered to by the Foundation