Development and Validation of Analytical Method for Aripiprazole and Escitalopram Oxalate by Simultaneous Equation Spectroscopic Method

2016 ◽  
Vol 6 (1) ◽  
pp. 41
Author(s):  
Divya Solanki ◽  
Hasumati Raj ◽  
Neelam Prajapati
Keyword(s):  
Analytical Method ◽  
Spectroscopic Method ◽  
Simultaneous Equation ◽  
Development And Validation ◽  
Validation Of Analytical Method

scholarly journals Development and validation of analytical method for Irbesartan and Atorvastatin by simultaneous equation spectroscopic method

2015 ◽  
Vol 1 (4) ◽  
pp. 194
Author(s):  
Paras B Virani ◽  
Rajanit Sojitra ◽  
Hasumati Raj ◽  
Vineet Jain
Keyword(s):  
Spectroscopic Method ◽  
Simultaneous Equation ◽  
Simultaneous Estimation ◽  
Limit Of Quantification ◽  
Limit Of Determination ◽  
Relative Standard ◽  
Acceptance Range ◽  
High Concentrations ◽  
Development And Validation ◽  
Validation Of Analytical Method

A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Irbesartan and atorvastatin in synthetic mixture using simultaneous equation Method. In this spectroscopic method, 226.00 nm and 246.00 nm wavelengths were selected for measurement of absorptivity. Both the drugs show linearity in a concentration range of 05-30 ?g/ml at their respective ?max. Accuracy, precision and recovery studies were done by QC samples covering lower, medium and high concentrations of the linearity range. The relative standard deviation for accuracy, precision studies were found to be within the acceptance range (<2%). The limit of determination was 0.033?g/ml and 0.125 ?g/ml for Irbesartan and atorvastatin, respectively. The limit of quantification was 0.1008 ?g/ml and 0.3792 ?g/ml for Irbesartan and atorvastatin, respectively. Recovery of Irbesartan and atorvastatin were found to be 99.75 % and 99.52% respectively confirming the accuracy of the proposed method. The proposed method is recommended for routine analysis since they are rapid, simple, accurate and also sensitive and specific by no heating and no organic solvent extraction.

scholarly journals Development and validation of analytical method by HPLC-DAD for determination of vasodilator active in pharmaceutical ophthalmic forms

2020 ◽  
Vol 41 ◽  
Author(s):  
Aina Liz Alves Cesar ◽  
Larissa Caldeira Navarro ◽  
Alaíde de Matos Silva ◽  
Rachel Oliveira Castilho ◽  
Gisele Assis Castro Goulart ◽  
...  
Keyword(s):  
Analytical Method ◽  
Development And Validation ◽  
Validation Of Analytical Method

scholarly journals Development and validation of analytical method for the estimation of nateglinide in rabbit plasma

2012 ◽  
Vol 2 (6) ◽  
pp. 492-498 ◽  
Author(s):  
Nihar Ranjan Pani ◽  
Lilakant Nath ◽  
Akhilesh Vikram Singh ◽  
Santosh Kumar Mahapatra
Keyword(s):  
Analytical Method ◽  
Rabbit Plasma ◽  
Development And Validation ◽  
Validation Of Analytical Method
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