Platelet-to-Lymphocyte Ratio as a Potential Indicator of Infection-Associated Emergency Visits of Renal Transplant Recipients

2019 ◽  
Author(s):  
Murat Muratoglu ◽  
◽  
Afsin Emre Kayipmaz ◽  
Cemil Kavalci ◽  
Mahir Kirnap ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Platelet To Lymphocyte Ratio ◽  
Emergency Visits ◽  
Lymphocyte Ratio ◽  
Potential Indicator

scholarly journals Neutrophil-to-Lymphocyte Ratio Predicts Mortality in Adult Renal Transplant Recipients with Severe Community-Acquired Pneumonia

Pathogens ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 913
Author(s):  
Yue Qiu ◽  
Ying Su ◽  
Guo-Wei Tu ◽  
Min-Jie Ju ◽  
Hong-Yu He ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Pneumonia Severity Index ◽  
Area Under The Curve ◽  
Community Acquired Pneumonia ◽  
Neutrophil To Lymphocyte Ratio ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Lymphocyte Ratio ◽  
Laboratory Test Results ◽  
Severe Community Acquired Pneumonia

Mortality of renal transplant recipients with severe community-acquired pneumonia (CAP) remains high, despite advances in critical care management. There is still a lack of biomarkers for predicting prognosis of these patients. The present study aimed to investigate the association between neutrophil-to-lymphocyte ratio (NLR) and mortality in renal transplant recipients with severe CAP. A total of 111 renal transplant recipients with severe CAP admitted to the intensive care unit (ICU) were screened for eligibility between 1 January 2009 and 30 November 2018. Patient characteristics and laboratory test results at ICU admission were retrospectively collected. There were 18 non-survivors (22.2%) among 81 patients with severe CAP who were finally included. Non-survivors had a higher NLR level than survivors (26.8 vs. 12.3, p < 0.001). NLR had the greatest power to predict mortality as suggested by area under the curve (0.88 ± 0.04; p < 0.0001) compared to platelet-to-lymphocyte ratio (0.75 ± 0.06; p < 0.01), pneumonia severity index (0.65 ± 0.08; p = 0.05), CURB-65 (0.65 ± 0.08; p = 0.05), and neutrophil count (0.68 ± 0.07; p < 0.01). Multivariate logistic regression models revealed that NLR was associated with hospital and ICU mortality in renal transplant recipients with severe CAP. NLR levels were independently associated with mortality and may be a useful biomarker for predicting poor outcome in renal transplant recipients with severe CAP.

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