scholarly journals Comparison of Biochemical Recurrence After Robot-assisted Laparoscopic Radical Prostatectomy with Volatile and Total Intravenous Anesthesia

2020 ◽  
Vol 17 (4) ◽  
pp. 449-456
Author(s):  
Na Young Kim ◽  
Won Sik Jang ◽  
Young Deuk Choi ◽  
Jung Hwa Hong ◽  
Sewon Noh ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0230290 ◽  
Author(s):  
Hou-Chuan Lai ◽  
Meei-Shyuan Lee ◽  
Kuen-Tze Lin ◽  
Yi-Hsuan Huang ◽  
Jen-Yin Chen ◽  
...  






BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jiwon Han ◽  
Young-Tae Jeon ◽  
Jung-Hee Ryu ◽  
Ah-Young Oh ◽  
Hwanik Kim ◽  
...  

Abstract Background Although red blood cells (RBC) transfusion is known to be significantly associated with biochemical recurrence in patients undergoing open prostatectomy, its influence on biochemical recurrence after robot-assisted laparoscopic radical prostatectomy remains unclear. Therefore, this study aimed to validate the effect of RBC transfusion on the 5-year biochemical recurrence in patients undergoing robot-assisted laparoscopic radical prostatectomy. Methods This study retrospectively analyzed the medical records of patients who underwent robot-assisted laparoscopic radical prostatectomy at single tertiary academic hospital between October 2007 and December 2014. Univariate and multivariate Cox proportional hazard regression analysis was performed to identify any potential variables associated with 5-year biochemical recurrence. Results A total of 1311 patients were included in the final analysis. Of these, 30 patients (2.3%) were transfused with RBC either during robot-assisted laparoscopic radical prostatectomy or during their hospital stay, which corresponded to 5-year biochemical recurrence of 15.7%. Multivariate Cox proportional hazard regression analysis showed that RBC transfusion had no influence on the 5-year biochemical recurrence. Variables including pathologic T stage (Hazard ratio [HR] 3.5, 95% confidence interval [CI] 2.4–5.1 p < 0.001), N stage (HR 2.3, 95% CI 1.5–3.7, p < 0.001), Gleason score (HR 2.4, 95% CI 1.8–3.2, p < 0.001), and surgical margin (HR 2.0, 95% CI 1.5–2.8, p < 0.001) were independently associated with the 5-year biochemical recurrence. Conclusions RBC transfusion had no significant influence on the 5-year biochemical recurrence in patients undergoing robot-assisted laparoscopic radical prostatectomy.



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