Limitations to survival for infants with hypoplastic left heart syndrome before and after transplant: The Loma Linda experience

1997 ◽  
Vol 7 (4) ◽  
pp. 180-186 ◽  
Author(s):  
Joyce Johnston ◽  
Richard Chinnock ◽  
Craig Zuppan ◽  
Anees Razzouk ◽  
Steven Gundry ◽  
...  
2011 ◽  
Vol 21 (S2) ◽  
pp. 28-37 ◽  
Author(s):  
Thieu Nguyen ◽  
Michelle Miller ◽  
Javier Gonzalez ◽  
Katherine Nardell ◽  
James Galas ◽  
...  

AbstractEchocardiography is critical in the assessment of patients with hypoplastic left heart syndrome. Fundamental techniques and standardised approaches are useful when evaluating patients with hypoplastic left heart syndrome prenatally, after birth, and before the Norwood operation (Stage 1); after the Norwood operation, before and after the superior cavopulmonary anastomosis (Stage 2); before and after the Fontan operation (Stage 3); and for chronic surveillance after the Fontan operation. From foetal assessment to ongoing surveillance after the Fontan procedure, echocardiography remains the primary technique for cardiac monitoring in this growing population of children and adults.


2013 ◽  
Vol 35 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Tetsuko Ishii ◽  
Doff B. McElhinney ◽  
David M. Harrild ◽  
Edward N. Marcus ◽  
David J. Sahn ◽  
...  

1997 ◽  
Vol 7 (4) ◽  
pp. 180-186
Author(s):  
Joyce K Johnston ◽  
Richard E Chinnock ◽  
Craig W Zuppan ◽  
Anees J Razzouk ◽  
Steven R Gundry ◽  
...  

Untreated, hypoplastic left heart syndrome is a lethal cardiac defect. Heart transplant has become an accepted therapeutic option for this condition. However, significant limitations to survival remain for infants with this condition who are referred for heart transplantation. Attention to the prevention, early detection, and management of common problems occurring at each stage of the transplantation process is important for improving survival rates. This study retrospectively reviewed the cases of 195 infants with hypoplastic left heart syndrome registered for heart transplantation at Loma Linda University Medical Center between November 1985 and July 1996 to determine causes of death. During the waiting period, progressive cardiac failure and complications from interventional procedures were the leading causes. In the early postoperative period, technical issues and acute graft failure were most important, whereas late deaths (more than 30 days after transplant) were most often related to rejection and posttransplant coronary artery disease.


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