scholarly journals The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
You Li ◽  
Pallavi Pillai ◽  
Fuyu Miyake ◽  
Harish Nair
Keyword(s):  
Systematic Review ◽  
Respiratory Syncytial Virus ◽  
Respiratory Infections ◽  
Meta Analysis ◽  
Acute Respiratory Infections ◽  
Syncytial Virus

scholarly journals Additional Diagnostic Yield of Adding Serology to PCR in Diagnosing Viral Acute Respiratory Infections in Kenyan Patients 5 Years of Age and Older

2012 ◽  
Vol 20 (1) ◽  
pp. 113-114 ◽  
Author(s):  
Daniel R. Feikin ◽  
M. Kariuki Njenga ◽  
Godfrey Bigogo ◽  
Barrack Aura ◽  
Stella Gikunju ◽  
...  
Keyword(s):  
Respiratory Infections ◽  
Diagnostic Yield ◽  
Epidemiologic Studies ◽  
Acute Respiratory Infections ◽  
Clinical Use ◽  
Paired Sample ◽  
Parainfluenza Viruses ◽  
Syncytial Virus ◽  
Etiologic Diagnosis

ABSTRACTThe role of serology in the setting of PCR-based diagnosis of acute respiratory infections (ARIs) is unclear. We found that acute- and convalescent-phase paired-sample serologic testing increased the diagnostic yield of naso/oropharyngeal swabs for influenza virus, respiratory syncytial virus (RSV), human metapneumovirus, adenovirus, and parainfluenza viruses beyond PCR by 0.4% to 10.7%. Although still limited for clinical use, serology, along with PCR, can maximize etiologic diagnosis in epidemiologic studies.

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