scholarly journals Prognostic Role of MicroRNA-21 in Non-small Cell Lung Cancer: a Meta-analysis

2012 ◽  
Vol 13 (5) ◽  
pp. 2329-2334 ◽  
Author(s):  
Xue-Lei Ma ◽  
Lei Liu ◽  
Xiao-Xiao Liu ◽  
Yun Li ◽  
Lei Deng ◽  
...  
PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0116771 ◽  
Author(s):  
Lei Li ◽  
Dan Liu ◽  
Zhi-Xin Qiu ◽  
Shuang Zhao ◽  
Li Zhang ◽  
...  

2020 ◽  
Vol 12 (3) ◽  
pp. 823-829
Author(s):  
Quanwa Bao ◽  
Feng Li ◽  
Houzhen Zheng ◽  
Shaobo Chen ◽  
Xiao Song

2013 ◽  
Vol 14 (6) ◽  
pp. 3607-3612 ◽  
Author(s):  
Cong Li ◽  
Hua-Jun Lu ◽  
Fei-Fei Na ◽  
Lei Deng ◽  
Jian-Xin Xue ◽  
...  

2020 ◽  
Author(s):  
Xiaoting Zhang ◽  
Huaning Kang ◽  
Guihong Chen ◽  
Xiaofeng Li

Abstract BackgroundRecent studies have shown that MicroRNAs can be used as potential biomarkers to the prognosis in non-small cell lung cancer (NSCLC). Hence, we conducted this meta-analysis to evaluate the prognostic role of microRNA let-7 in NSCLC patients.MethodsPubMed, Web of Science, Medline and the Cochrane Library were searched for relevant studies. Eligible studies were met specific inclusion and exclusion criteria. Stata 15.1 was used to calculate the pooled parameters.ResultsA total of 11 studies involving 2278 NSCLC patients were included in this meta-analysis. Subgroup analyses established that the heterogeneity was connected with ethnicity and follow-up time. The results suggested that the low expression of microRNA let-7 indicates a poor overall survival rate, with a hazard ratio value of 0.99 (95% CI: 0.64-1.34, P <0.05).ConclusionsLow expression of microRNA let-7 is closely related to the poor prognosis of NSCLC, so microRNA let-7 may become a new biomarker to evaluate the prognosis of NSCLC patients.


2018 ◽  
Vol 9 (5) ◽  
pp. 640-645 ◽  
Author(s):  
Bing Tong ◽  
Yan Xu ◽  
Jing Zhao ◽  
Minjiang Chen ◽  
Wei Zhong ◽  
...  

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