Administration of Neutral Protamine Hagedorn Insulin at Bedtime versus with Dinner in Type 1 Diabetes Mellitus To Avoid Nocturnal Hypoglycemia and Improve Control

2002 ◽  
Vol 136 (7) ◽  
pp. 504 ◽  
Author(s):  
Carmine G. Fanelli ◽  
Simone Pampanelli ◽  
Francesca Porcellati ◽  
Paolo Rossetti ◽  
Paolo Brunetti ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Dylan Kelly ◽  
Jill K. Hamilton ◽  
Michael C. Riddell

Background. Acute hypo- and hyperglycemia causes cognitive and psychomotor impairment in individuals with type 1 diabetes mellitus (T1DM) that may affect sports performance.Objective. To quantify the effect of concurrent and antecedent blood glucose concentrations on sports skills and cognitive performance in youth with T1DM attending a sports camp.Design/Methods. 28 youth (ages 6–17 years) attending a sports camp carried out multiple skill-based tests (tennis, basketball, or soccer skills) with glucose monitoring over 4 days. Glucose levels at the time of testing were categorized as (a) hypoglycemic (<3.6 mM); (b) within an acceptable glycemic range (3.6–13.9 mM); or (c) hyperglycemic (>13.9 mM).Results. Overall, sports performance skill was~20% lower when glucose concentrations were hypoglycemic compared to either acceptable or hyperglycemic at the time of skill testing (). During Stroop testing, “reading” and “color recognition” also degraded during hypoglycemia, while “interference” scores improved (). Nocturnal hypoglycemia was present in 66% of subjects, lasting an average of 84 minutes, but this did not affect sports skill performance the following day.Conclusions. Mild hypoglycemia markedly reduces sports skill performance and cognition in young athletes with T1DM.


2014 ◽  
Vol 60 (10) ◽  
pp. 1267-1270 ◽  
Author(s):  
Tze Ping Loh ◽  
Shao Feng Mok ◽  
Shih Ling Kao ◽  
Eric Khoo ◽  
Ah Chuan Thai

2004 ◽  
Vol 41 (2) ◽  
pp. 33-37 ◽  
Author(s):  
I. Radan ◽  
E. Rajer ◽  
N. Uršič Bratina ◽  
D. Neubauer ◽  
C. Kržišnik ◽  
...  

PLoS Medicine ◽  
2007 ◽  
Vol 4 (2) ◽  
pp. e69 ◽  
Author(s):  
Bernd Schultes ◽  
Kamila Jauch-Chara ◽  
Steffen Gais ◽  
Manfred Hallschmid ◽  
Eva Reiprich ◽  
...  

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