ISLET-CELL TUMORS AND PEPTIC ULCERS: CASE REPORT OF THE ZOLLINGER-ELLISON SYNDROME

1960 ◽  
Vol 53 (6) ◽  
pp. 1180 ◽  
Keyword(s):  
Case Report ◽  
Islet Cell ◽  
Peptic Ulcers ◽  
Islet Cell Tumors ◽  
Zollinger Ellison Syndrome

Ulcerogenic Tumors of the Pancreas

1968 ◽  
Vol 26 ◽  
pp. 186-187
Author(s):  
J. C. Garancis ◽  
J. F. Kuzma ◽  
S. D. Wilson ◽  
E. H. Ellison
Keyword(s):  
Endoplasmic Reticulum ◽  
Tumor Cells ◽  
Islet Cell ◽  
Disease Process ◽  
Central Core ◽  
Islet Cell Tumors ◽  
Opaque Zone ◽  
Granular Form ◽  
Zollinger Ellison Syndrome

It has been proposed that a gastrin-like hormone elaborated by non-beta islet tumors of the pancreas may be responsible for a fulminating ulcer diathesis. Subsequently, a potent gastric secretagogue was isolated from ulcerogenic tumors of the pancreas. This disease process is known now as “Zollinger-Ellison syndrome”.In our studies of two cases of Zollinger-Ellison syndrome, pancreatic lesions were identified as alpha islet cell tumors (Fig. 1). Tumor cells were fairly uniform. The sizes of the alpha granules were not significantly different, but their number and distribution varied greatly from one cell to another. Each granule consisted of a round, highly dense central core, separated from the limiting membrane by an opaque zone. The granular form of the endoplasmic reticulum was particularly prominent. Numerous mitochondria, round or elongated, were dispersed throughout the cytoplasm. Individual or clusters of lysosomes were observed in the majority of cells.

Zollinger-Ellison Syndrome in a Nineyear -old Child: A Case Report and Review of this Entity in Childhood

PEDIATRICS ◽  
1971 ◽  
Vol 47 (3) ◽  
pp. 594-598
Author(s):  
Richard M. Buchta ◽  
J. M. Kaplan
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Clinical Data ◽  
Islet Cell ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Gastric Hypersecretion ◽  
Zollinger Ellison Syndrome ◽  
History Of ◽  
Epigastric Abdominal Pain

In 1955, Zollinger and Ellison1 described a syndrome consisting of peptic ulceration, marked gastric hypersecretion, and non-beta islet cell tumor of the pancreas. Although there have been over 300 cases in the adult literature2-5 only 19 patients, 16 years old or younger have been reported. We add one more child to this growing list and review the clinical data of the known cases described. Case Report The patient (R.L.) was a 9-year-old Negro male with a 7-month history of intermittent episodes of mid-epigastric abdominal pain. The pain was somewhat relieved by eating, or the use of antispasmodics. During this period of time, the child had occasional episodes of vomiting, but no melena or hematemesis.

scholarly journals A case report of multiple nonfunctioning islet cell tumors of the pancreas and aberrant pancreas of jejunum.

1986 ◽  
Vol 19 (11) ◽  
pp. 2292-2295
Author(s):  
Kunio TSUKADA ◽  
Hideo KIKUTA ◽  
Masuo IIZUKA ◽  
Kunio TORIYA ◽  
Masamichi WATANABE
Keyword(s):  
Case Report ◽  
Islet Cell ◽  
Islet Cell Tumors ◽  
Aberrant Pancreas

Arteriographic Demonstration and Successful Removal of Metastatic Islet Cell Tumors in Liver: A Case Report

Diabetes ◽  
1967 ◽  
Vol 16 (8) ◽  
pp. 598-599 ◽  
Author(s):  
J. Smrcka ◽  
J. Bret ◽  
J. Hauer ◽  
V. Polomis
Keyword(s):  
Case Report ◽  
Islet Cell ◽  
Islet Cell Tumors ◽  
Successful Removal

scholarly journals Nonfunctional Islet Cell Tumor of the Pancreas in a Patient with Tuberous Sclerosis: A Case Report with Literature Review

2014 ◽  
Vol 4 ◽  
pp. 3 ◽  
Author(s):  
Aysegul Cansu ◽  
Ali Ahmetoglu ◽  
Sibel Kul ◽  
Dilek Uzman ◽  
Safak Ersoz
Keyword(s):  
Case Report ◽  
Tuberous Sclerosis ◽  
Islet Cell ◽  
Histopathological Examination ◽  
Islet Cell Tumor ◽  
Large Mass ◽  
Cell Tumor ◽  
Islet Cell Tumors ◽  
Appropriate Treatment ◽  
Subependymal Nodules

Islet cell tumors (ICTs) are rare tumors of the pancreas. Association of this type of tumor with tuberous sclerosis is extremely rare. Only 13 cases of pancreatic ICT with tuberous sclerosis have so far been documented in the literature. However, awareness of the association of tuberous sclerosis and ICT is important for early diagnosis and appropriate treatment of this condition. This article presents the case of a 63-year-old female with angiomyolipoma (AML) of the kidney and liver, calcified subependymal nodules and a large mass in the pancreas, which was proven to be an ICT on histopathological examination.

Zollinger-Ellison syndrome in a patient with multiple carcinoid-islet cell tumors of the duodenum

1968 ◽  
Vol 115 (2) ◽  
pp. 177-184 ◽  
Author(s):  
James C. Thompson ◽  
Frank M. Hirose ◽  
Carlos A.E. Lemmi ◽  
Warren D. Davidson
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumors ◽  
Zollinger Ellison Syndrome

Gastrinoma: a retrospective study of four cases (1985-1995)

1997 ◽  
Vol 33 (6) ◽  
pp. 524-527 ◽  
Author(s):  
RA Green ◽  
CL Gartrell
Keyword(s):  
Veterinary Medicine ◽  
Retrospective Study ◽  
Islet Cell ◽  
Serum Gastrin ◽  
Elevated Serum ◽  
Islet Cell Tumors ◽  
Zollinger Ellison Syndrome ◽  
Exploratory Surgery

Islet-cell tumors of the pancreas, such as gastrinoma, are rare in veterinary medicine. Patients with gastrinoma or Zollinger-Ellison syndrome have elevated serum gastrin levels which ultimately cause gastrointestinal ulcerations. Due to their small size, gastrinomas are a challenge to localize prior to surgery. In veterinary medicine, exploratory surgery with biopsy for histopathology confirms the diagnosis of gastrinoma. This is a retrospective study of four dogs with gastrinoma.

Zollinger-Ellison Syndrome: A Case Report

1999 ◽  
Vol 41 (6) ◽  
pp. 1173 ◽  
Author(s):  
Dong Jin Jung ◽  
Hyun Kwon Ha ◽  
Pyo Nyun Kim ◽  
Moon Gyu Lee ◽  
Yong Ho Auh
Keyword(s):  
Case Report ◽  
Zollinger Ellison Syndrome

Islet Cell Tumors of the Pancreas

1994 ◽  
Vol 23 (1) ◽  
pp. 53-65 ◽  
Author(s):  
Rena Vassilopoulou-Sellin ◽  
Jaffer Ajani
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumors
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