scholarly journals Obstetric and perinatal outcomes of dizygotic twin pregnancies resulting from in vitro fertilization versus spontaneous conception: a retrospective study

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6638 ◽  
Author(s):  
Hua Chen ◽  
Ying Wan ◽  
Haitao Xi ◽  
Weijue Su ◽  
Jing Cheng ◽  
...  

This study was designed to to assess perinatal and neonatal outcomes of dizygotic twin pregnancies conceived naturally or by in vitro fertilization (IVF). After strict selection, the study included 470 dizygotic twin pregnancies. There were 249 resulting from IVF treatments and 221 conceiving spontaneously. After adjusting maternal age and primiparity, the results showed that there were no significant differences between the two groups (P > 0.05) in terms of maternal antenatal complications and neonatal outcomes. In conclusion, our study does not reveal increased risks for pregnancy-related complications and adverse neonatal outcomes in dizygotic twin pregnancies following IVF treatments. With these fundamental data, this study could provide a reference for perinatal care and clinical assisted reproductive technology (ART) treatment and help to inform infertile parents about the potential risks of IVF treatments.

Author(s):  
Chetan Yadav ◽  
Charu Yadav

Background: In-vitro fertilization or Assisted reproductive techniques (ART) is the most advanced technique of infertility treatment. In-vitro fertilization (IVF) has helped couples all over the world. However, the use of IVF has raised significant concern about the outcome of resulting pregnancies and the health of the newborns. There is a range of possible factors associated with the treatment that may contribute to potential adverse outcomes. Thus, the study was conducted to analyze the neonatal outcomes of children born by ART in the Indian context.Methods: The neonatal characteristics and complications of the live-born infants through IVF at Army Hospital R and R were analyzed in this study between March 2019 to February 2020.Results: Total 231 babies were born to the study group cases. 126 (54.54%) were singletons, 102 (44.16%) were of twin pregnancies and 1.3% were triplets. There were 65.36% term and 34.63% preterm. Of the 231 IVF neonates, 58 needed neonatal intensive care. There were 219 (94.8%) survivors, while 12 (5.2%) did not survive a week. The 16 (6.92%) survivors needed readmissions mainly due to hyperbilirubinemia. There were 106 (45.8%) babies whose weight was less than 2 kg.Conclusions: Infertility cases are usually older, and this is one reason for increased pregnancy and newborn infant complications. Neonates born through IVF appeared to be at higher risk of multiple births, prematurity, low birth weight, and other disabilities.


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