scholarly journals Basal Cell Carcinoma and Sebaceoma Within Nevus Sebaceous of the Scalp

Cureus ◽  
2021 ◽  
Author(s):  
Katherine David ◽  
Mandy Alhajj ◽  
Jeffrey Parks ◽  
Rabail Aslam ◽  
Jessica Sigel
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Nevus Sebaceous

CD10, TDAG51, CK20, AR, INSM1, and Nestin Expression in the Differential Diagnosis of Trichoblastoma and Basal Cell Carcinoma

2018 ◽  
Vol 27 (1) ◽  
pp. 19-27 ◽  
Author(s):  
Cem Leblebici ◽  
Buket Bambul Sığırcı ◽  
Canan Kelten Talu ◽  
Sevim Baykal Koca ◽  
Gülben Erdem Huq
Keyword(s):  
Differential Diagnosis ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
The Other ◽  
Cytokeratin 20 ◽  
Nestin Expression ◽  
The Difference ◽  
Nevus Sebaceous ◽  
Sensitive Marker

Background. Trichoblastoma (TB) and basal cell carcinoma (BCC) are 2 different neoplasms composed of basaloid cells and have overlapping histopathological features. We compared the immunoexpression of CD10, T-cell death-associated gene 51 (TDAG51), cytokeratin 20 (CK20), androgen receptor (AR), insulinoma-associated protein 1 (INSM1), and nestin for the differential diagnosis of these tumors. Materials and Methods. We assessed a total of 27 BCC and 27 TB cases, including 4 TB lesions in nevus sebaceous and 3 malignant TB lesions for CD10, TDAG51, CK20, AR, INSM1, and nestin expression. Results. Staining for CK20, TDAG51, INSM1, and stromal CD10 was significantly more common in TB cases than in BCC cases ( P < .001). Epithelial CD10 and AR staining was significantly more common in BCC cases than in TB cases ( P < .001). The difference between the groups for nestin staining was not significant ( P > .05). Stromal CD10 staining was the most sensitive marker (96.3%) and INSM1 the least sensitive (55.6%) marker for TB. TDAG51 showed 100% specificity for TB. A larger number of CK20 positive cells was found in the cases associated with nevus sebaceous than in the other TBs. Conclusion. All the selected markers except nestin were useful for the differential diagnosis between TB and BCC. CD10 and TDAG51 were more useful than the other markers. The use of CK20 could be preferred in nevus sebaceous lesions. INSM1 was less effective in highlighting Merkel cells within the lesion than CK20.

scholarly journals Management of Nevus Sebaceous and the Risk of Basal Cell Carcinoma: An 18-Year Review

2009 ◽  
Vol 26 (6) ◽  
pp. 676-681 ◽  
Author(s):  
Heather Rosen ◽  
Birgitta Schmidt ◽  
Herman P. Lam ◽  
John G. Meara ◽  
Brian I. Labow
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Nevus Sebaceous

scholarly journals Coexisting Basal Cell Carcinoma and Squamous Cell Carcinoma in Congenital Nevus Sebaceous

2018 ◽  
Vol 2 (3) ◽  
pp. 181-185
Author(s):  
Jordan Rosen ◽  
Katherine Nolan ◽  
Noah Shaikh ◽  
Les Rosen ◽  
Martin Zaiac
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Squamous Cell Carcinomas ◽  
Malignant Neoplasms ◽  
Rare Occurrence ◽  
Unique Case ◽  
Nevus Sebaceous

Nevus sebaceous is a congenital epidermal hamartoma characterized by hyperplastic changes to the epidermis and adnexa. Nevus sebaceous is associated with an elevated risk of cutaneous neoplasms, most often benign; however, malignant neoplasms, most notably basal cell carcinoma, can also present in these patients. Although a rare occurrence, more often affecting adult patients, squamous cell carcinomas have also been reported to arise at the site of pre-existing nevus sebaceous. Herein we report a unique case of a patient with basal cell carcinoma and squamous cell carcinoma arising concurrently in the same nevus sebaceous.

Sebaceous carcinoma and basal cell carcinoma arising within nevus sebaceous on the face—A rare entity with dermatoscopic findings

2020 ◽  
Vol 33 (4) ◽  
Author(s):  
Seher Bostanci ◽  
Bengu Nisa Akay ◽  
Cengizhan Erdem ◽  
Aylin Okcu Heper ◽  
Banu Farabi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Sebaceous Carcinoma ◽  
Rare Entity ◽  
The Face ◽  
Nevus Sebaceous

Basal Cell Carcinoma Arising in Nevus Sebaceous during Childhood

2008 ◽  
Vol 25 (6) ◽  
pp. 616-619 ◽  
Author(s):  
Aslı Altaykan ◽  
Sibel Ersoy-Evans ◽  
Gül Erkin ◽  
Özay Özkaya
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Nevus Sebaceous

Response to Letter on “Management of Nevus Sebaceous and the Risk of Basal Cell Carcinoma: An 18-year Review”

2011 ◽  
Vol 28 (1) ◽  
pp. 82-82
Author(s):  
HEATHER ROSEN ◽  
BIRGITTA SCHMIDT ◽  
HERMAN P. LAM ◽  
JOHN G. MEARA ◽  
BRIAN I. LABOW
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Nevus Sebaceous
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