scholarly journals First Case of Autoimmune Hemolytic Anemia Associated With COVID-19 Infection in Sri Lanka: A Case Report

Cureus ◽  
2021 ◽  
Author(s):  
Vaishnavi Arunpriyandan ◽  
Somasuriyam Kumanan ◽  
Mayurathan Pakkiyaretnam
Author(s):  
M Wan ◽  
A Ganesh ◽  
C Grassi ◽  
A Demchuk

Background: Mixed autoimmune hemolytic anemia (mAIHA) is a rare autoimmune disorder that results in hemolysis with thrombotic complications like ischemic stroke. This is the first case report of cerebral microbleeds secondary to mAIHA. Methods: A literature review of mAIHA and cerebral microbleeds was conducted using the PubMed and Ovid MEDLINE databases from 1980 to 2021. Results: A 76 year old male with congenital deafness and rheumatoid arthritis presented with diffuse livedo reticularis and abdominal pain. He had fulminant hemolysis with new neurologic deficits and altered mental status. CT/CTA of the head and neck were unremarkable. MR brain revealed extensive cerebral microbleeds and multi-territory ischemic strokes. He was diagnosed with mAIHA, started on pulse methylprednisolone, and had no further microbleeds on follow-up MRI. From his clinical picture, common causes of cerebral microbleeds were ruled out such as cerebral amyloid angiopathy and hypertension. The pathogenesis of his microbleeds may be from concomitant severe hypoxia or a prothrombotic state, both previously reported in the literature. Conclusions: This is the first case report of extensive cerebral microbleeds secondary to mAIHA. When a patient develops acute neurologic deficits in the context of mAIHA, extensive cerebral microbleeds may be present possibly due to concomitant severe hypoxia versus a prothrombotic state.


2014 ◽  
Vol 25 (1) ◽  
Author(s):  
Hasan M. Isa ◽  
◽  
Lina F. Al Ali ◽  
Afaf M. Mohamed ◽  
Rawia M. Hamad ◽  
...  

2021 ◽  
pp. 13-14
Author(s):  
Jessica Pereira ◽  
Aparna Pai

Lymphoproliferative disorders encompass a group of diseases with a highly variable clinical course. This is a case report of a patient who presented with haemolytic anemia initially and was subsequently diagnosed as a chronic lymphoproliferative disorder. He was treated with Rituximab to which he showed a favourable response.


2019 ◽  
Author(s):  
ANA GABRIELA CARDOSO FERRAZ ◽  
NARA LÍDIA FONSECA DE OLIVEIRA ◽  
YARA DE PAULA DUARTE LACERDA ◽  
ANA CAROLINA OLIVEIRA E SILVA MONTANDOM ◽  
NILZIO ANTÔNIO DA SILVA ◽  
...  

2014 ◽  
pp. 328-331
Author(s):  
Quan Le Zhang ◽  
Li Juan Jia ◽  
Jin Biao Zhang ◽  
Wei Min Li ◽  
Yuan Kai Bo ◽  
...  

2019 ◽  
Vol 12 ◽  
pp. 1179545X1989457
Author(s):  
Tahseen Hamamyh ◽  
Mohamed A Yassin

Autoimmune hemolytic anemia is one of the differential diagnoses for anemia in patients with lymphoproliferative neoplasia, such as chronic lymphocytic leukemia, who experience sudden drop in hemoglobin. The association between autoimmune hemolytic anemia and chronic myeloid leukemia on the contrary is unusual. Here we present a patient with a background of chronic myeloid leukemia treated previously with Tyrosine Kinase Inhibitors, then developed autoimmune hemolysis simultaneously with chronic myeloid leukemia relapse. Hemolysis was treated with steroids with good response.


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