scholarly journals Selective Serotonin Reuptake-Inhibitors for Symptom-Based Treatment of Borderline Personality Disorders in Older Adults: An International Delphi Study

2021 ◽  
Vol 19 (1) ◽  
pp. 53-62
Author(s):  
Julie Schulkens ◽  
Nina Bergs ◽  
Theo Ingenhoven ◽  
Erlene Rosowsky ◽  
Sebastiaan van Alphen ◽  
...  
2016 ◽  
Vol 33 (S1) ◽  
pp. S473-S473 ◽  
Author(s):  
S. Petrykiv ◽  
L. de Jonge ◽  
M. Arts

IntroductionSelective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed antidepressants with generally fewer side effects than most other types of antidepressants. However, in frail elderly, the use of SSRIs was anecdotally reported as a potential cause of a delirium.ObjectivesTo present a case of citalopram-induced delirium in an older adult diagnosed with late-life depression.AimsTo review available literature on SSRI-induced delirium.MethodsA case report is presented and discussed, followed by a literature review.ResultsSeven published cases of SSRI-induced delirium in older adults (> 60 years) were found while searching through Pubmed and Embase. Our case of a 75-year-old female is also included in this report. This patient was ambulatory treated with citalopram 20 mg per os against depressive symptoms and she developed a delirium four days after the initiation of the therapy. Blood tests were normal and CT scan showed no significant findings. No other medical evidence was found that could explain her delirium. Her symptoms finally resolved after discontinuation of citalopram.ConclusionThe on- and off-treatment side-effect correlation by a segregate oral use of citalopram strongly suggests that SSRIs may have the potential to cause a delirium, especially in frail elderly. Further research on this topic is needed.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2014 ◽  
Vol 48 (6) ◽  
pp. 857-865 ◽  
Author(s):  
Antônio Ignácio de Loyola Filho ◽  
Érico Castro-Costa ◽  
Josélia Oliveira Araújo Firmo ◽  
Sérgio Viana Peixoto

OBJECTIVE To analyze the trends and factors associated with the antidepressant use among older adults. METHODS This population-based study evaluated older adults in 1997 (n = 351, baseline) and the survivors at the 15th follow-up year (n = 462, in 2012) among the aging cohort of Bambuí. The prevalence of antidepressant use was estimated, and the most commonly used antidepressants each year were identified. Prevalence ratios with 95% confidence intervals were estimated using Poisson regression with robust variance to investigate differences in the prevalence of use between 1997 and 2012. RESULTS The overall consumption of antidepressants (PR = 2.87, 95%CI 1.94;4.25) and of selective serotonin reuptake inhibitors (PR = 7.50, 95%CI 3.74;15.02) was significantly higher in 2012. However, no significant difference was observed in the use of tricyclic antidepressants between the two cohorts (PR = 0.89, 95%CI 0.49;1.62). In the 2012 cohort, antidepressant use was associated with females, increased age, increased income (≥ 4 minimum wages), self-assessment of health as reasonable, and attending ≥ 5 medical consultations in the last 12 months. CONCLUSIONS The increased consumption of antidepressants in the period due to increased use of selective serotonin reuptake inhibitors was consistent with results observed in international studies of different population groups and contexts. The positive correlation observed between antidepressant use and family income may be a warning of possible inequalities in access to mental health services.


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