scholarly journals Mechanical thrombectomy in patients with acute ischemic stroke: a cost-utility analysis

CMAJ Open ◽  
2016 ◽  
Vol 4 (2) ◽  
pp. E316-E325 ◽  
Author(s):  
X. Xie ◽  
A. Lambrinos ◽  
B. Chan ◽  
I. A. Dhalla ◽  
T. Krings ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Mechanical Thrombectomy ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis

scholarly journals Cost-utility analysis of mechanical thrombectomy between 6 and 24 hours in acute ischemic stroke

2019 ◽  
Vol 15 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Elena Pizzo ◽  
Maureen Dumba ◽  
Kyriakos Lobotesis
Keyword(s):  
Ischemic Stroke ◽  
Medical Treatment ◽  
Acute Ischemic Stroke ◽  
Mechanical Thrombectomy ◽  
Cost Effective ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Life Years ◽  
The Uk

Background Recently, two randomized controlled trials demonstrated the benefit of mechanical thrombectomy performed between 6 and 24 h in acute ischemic stroke. The current economic evidence is supporting the intervention only within 6 h, but extended thrombectomy treatment times may result in better long-term outcomes for a larger cohort of patients. Aims We compared the cost-utility of mechanical thrombectomy in addition to medical treatment versus medical treatment alone performed beyond 6 h from stroke onset in the UK National Health Service (NHS). Methods A cost-utility analysis of mechanical thrombectomy compared to medical treatment was performed using a Markov model that estimates expected costs and quality-adjusted life years (QALYs) over a 20-year time horizon. We present the results of three models using the data from the DEFUSE 3 and DAWN trials and evidence from published sources. Results Over a 20-year period, the incremental cost per QALY of mechanical thrombectomy was $1564 (£1219) when performed after 12 h from onset, $5253 (£4096) after 16 h and $3712 (£2894) after 24 h. The probabilistic sensitivity analysis demonstrated that thrombectomy had a 99.9% probability of being cost-effective at the minimum willingness to pay for a QALY commonly used in the UK. Conclusions The results of this study demonstrate that performing mechanical thrombectomy up to 24 h from acute ischemic stroke symptom onset is still cost-effective, suggesting that this intervention should be implemented by the NHS on the basis of improvement in quality of life as well as economic grounds.

scholarly journals Cost-Utility Analysis of Mechanical Thrombectomy Using Stent Retrievers in Acute Ischemic Stroke

Stroke ◽  
2015 ◽  
Vol 46 (9) ◽  
pp. 2591-2598 ◽  
Author(s):  
Jeban Ganesalingam ◽  
Elena Pizzo ◽  
Stephen Morris ◽  
Tom Sunderland ◽  
Diane Ames ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Mechanical Thrombectomy ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Stent Retrievers

scholarly journals Cost–Utility Analysis of Magnetic Resonance Imaging Management of Patients with Acute Ischemic Stroke in a Spanish Hospital

2015 ◽  
Vol 4 (1) ◽  
pp. 25-37 ◽  
Author(s):  
Elizabeth Parody ◽  
Salvador Pedraza ◽  
María M. García-Gil ◽  
Carlos Crespo ◽  
Joaquín Serena ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Acute Ischemic Stroke ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Resonance Imaging ◽  
Utility Analysis ◽  
Spanish Hospital

Cost-Utility Analysis of Hub-and-Spoke Telestroke Networks for the Management of Acute Ischemic Stroke from a Societal Perspective (P05.244)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P05.244-P05.244
Author(s):  
B. Demaerschalk ◽  
J. Switzer ◽  
J. Xie ◽  
L. Fan ◽  
K. Villa ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Societal Perspective ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Hub And Spoke
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