scholarly journals Validated Hptlc Method for Simultaneous Determination of Ceftriaxone Sodium and Tazobactam Sodium in Combined Dosage Form

2014 ◽  
Vol 9 (2) ◽  
pp. 60-65 ◽  
Author(s):  
Mr. Sanjay S. Malgundkar ◽  
◽  
Dr. Saira Mulla
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Ceftriaxone Sodium ◽  
Hptlc Method

VALIDATED HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF OLMESARTAN MEDOXIMIL AND METOPROLOL SUCCINATE IN TABLET DOSAGE FORM

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (10) ◽  
pp. 13-17
Author(s):  
V. V Kunjir ◽  
◽  
S. B. Jadhav ◽  
A. J Purkar ◽  
P. D. Chaudhari
Keyword(s):  
Simultaneous Determination ◽  
Mobile Phase ◽  
High Performance ◽  
Dosage Form ◽  
Chromatographic Method ◽  
Metoprolol Succinate ◽  
Ich Guidelines ◽  
Tablet Dosage ◽  
Hptlc Method

A high performance thin layer chromatographic method has been developed for the simultaneous determination of olmesartan medoximil and metoprolol succinate from tablet dosage form. The mobile phase consisting of water-methanol-ammonium sulphate (4.5:4.5:1.5 v/v/v) and wavelength of detection 233 nm was used. The developed method was validated as per ICH guidelines.

scholarly journals A Simple and Sensitive HPTLC Method for Simultaneous Determination of Abacavir Sulphate and Lamivudine in Tablet Dosage Form

2009 ◽  
Vol 8 (4) ◽  
pp. 187
Author(s):  
P. K. Saini ◽  
C. L. Jain ◽  
R. M. Singh ◽  
S. C. Mathur ◽  
G. N. Singh ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Tablet Dosage ◽  
Hptlc Method

scholarly journals Stability-indicating HPTLC method for simultaneous determination of nateglinide and metformin hydrochloride in pharmaceutical dosage form

2011 ◽  
Vol 19 (4) ◽  
pp. 221-231 ◽  
Author(s):  
Asha Byju Thomas ◽  
Shrikrushna Digambar Patil ◽  
Rabindra Kumar Nanda ◽  
Lata Prasad Kothapalli ◽  
Shital Shridhar Bhosle ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Metformin Hydrochloride ◽  
Pharmaceutical Dosage Form ◽  
Stability Indicating ◽  
Hptlc Method

scholarly journals A NOVEL HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF CO-ENZYME Q10 AND α-TOCOPHEROL IN BULK AND PHARMACEUTICAL FORMULATION

2018 ◽  
Vol 10 (10) ◽  
pp. 134 ◽  
Author(s):  
Manasi B. Kulkarni ◽  
Anagha M. Joshi ◽  
Rohini V. Patil
Keyword(s):  
Ethyl Acetate ◽  
Simultaneous Determination ◽  
Mobile Phase ◽  
Dosage Form ◽  
Fixed Dose ◽  
Simultaneous Quantification ◽  
Rf Values ◽  
Hptlc Method ◽  
Detection And Quantification

Objective: HPTLC Method for Simultaneous quantification of co-enzyme Q10 and α-tocopherol in bulk and capsule dosage form was developed and validated as per International Conference on Harmonization [(ICH) Q2 (R1)] guideline.Methods: The chromatograms were developed using a mobile phase of Toluene: ethyl acetate: chloroform (10:1:2 v/v/v) on Pre-coated silica 60F 254 plates and quantified by densitometric absorbance mode at 280 nm.Results: The Rf values were 0.77 and 0.87 for co-enzyme Q10 and α-tocopherol, respectively. The linearity of the method was found to be in the concentration range of 0.6µg-1.8 µg/band for α-tocopherol and 2 µg-6 µg/band for co-enzyme Q10. The limits of detection and quantification were 0.3154 and 0.9559 µg/band for α-tocopherol and 3.441 and 10.42 µg/band for co-enzyme Q10.Conclusion: Developed densitometric method was found to be robust, precise, accurate, and rapid and can be used to analyse fixed-dose capsule samples of co-enzyme Q10 and α-tocopherol.

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