bovine pancreatic trypsin inhibitor
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scholarly journals BPTI folding revisited: switching a disulfide into methylene thioacetal reveals a previously hidden path

2018 ◽  
Vol 9 (21) ◽  
pp. 4814-4820 ◽  
Author(s):  
Reem Mousa ◽  
Shifra Lansky ◽  
Gil Shoham ◽  
Norman Metanis
Keyword(s):  
Protein Structure ◽  
Protein Stability ◽  
Disulfide Bond ◽  
Trypsin Inhibitor ◽  
Biological Function ◽  
Bovine Pancreatic Trypsin Inhibitor ◽  
Folding Mechanism ◽  
Pancreatic Trypsin Inhibitor ◽  
Model Protein

The folding mechanism of the model protein bovine pancreatic trypsin inhibitor was revisited. By switching the solvent exposed disulfide bond with methylene thioacetal we uncovered a hidden pathway in its folding mechanism. In addition, this moiety enhanced protein stability while fully maintaining the protein structure and biological function.

Bovine pancreatic trypsin inhibitor immobilized onto sepharose as a new strategy to purify a thermostable alkaline peptidase from cobia ( Rachycentron canadum ) processing waste

2016 ◽  
Vol 1033-1034 ◽  
pp. 210-217 ◽  
Author(s):  
Renata Cristina da Penha França ◽  
Caio Rodrigo Dias Assis ◽  
Juliana Ferreira Santos ◽  
Ricardo José Soares Torquato ◽  
Aparecida Sadae Tanaka ◽  
...  
Keyword(s):  
Trypsin Inhibitor ◽  
Bovine Pancreatic Trypsin Inhibitor ◽  
Processing Waste ◽  
Rachycentron Canadum ◽  
New Strategy ◽  
Pancreatic Trypsin Inhibitor

scholarly journals Bovine pancreatic trypsin inhibitor is a new antifungal peptide that inhibits cellular magnesium uptake

2014 ◽  
Vol 92 (6) ◽  
pp. 1188-1197 ◽  
Author(s):  
Mark R. Bleackley ◽  
Brigitte M. Hayes ◽  
Kathy Parisi ◽  
Tamana Saiyed ◽  
Ana Traven ◽  
...  
Keyword(s):  
Trypsin Inhibitor ◽  
Bovine Pancreatic Trypsin Inhibitor ◽  
Antifungal Peptide ◽  
Magnesium Uptake ◽  
Pancreatic Trypsin Inhibitor

scholarly journals Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability?

FEBS Journal ◽  
2013 ◽  
Vol 280 (22) ◽  
pp. 5750-5763 ◽  
Author(s):  
Tamás Molnár ◽  
Judit Vörös ◽  
Bálint Szeder ◽  
Kornél Takáts ◽  
József Kardos ◽  
...  
Keyword(s):  
Trypsin Inhibitor ◽  
Bovine Pancreatic Trypsin Inhibitor ◽  
Pancreatic Trypsin Inhibitor ◽  
Extreme Stability
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