Interoceptive signals give rise to subjective feeling states that can drive motivational and behavioral responses. In the context of alcohol use behaviors, interoceptive signals may shape subjective alcohol experiences, and thereby support bio-behavioral mechanisms of drinking behavior change. This study examined the acute effects of alcohol on participants’ interoceptive sensitivity, and determined whether pharmacologically induced changes in heart beat detection correlate with subjective alcohol effects, craving and expectancies.Participants completed a two-session, double-blind placebo controlled experiment (n=31). Participants consumed a beverage containing 0.4g/kg of alcohol or a placebo. They also completed measurements of alcohol expectancies at baseline, and alcohol-induced changes in mood, craving and light-headedness. Interoceptive sensitivity was measured using the heartbeat discrimination task prior to and following beverage administration, yielding indices of interoceptive accuracy, confidence and meta-cognition. Alcohol administration increased interoceptive accuracy compared to baseline and placebo; and those changes in interoception negatively correlated with negative alcohol expectancies. Further, changes in interoception positively correlated with perceived light-headedness and positive mood after alcohol administration, whereas null effects were found for craving. In the placebo condition, null results were obtained. Alcohol is well established to change bodily states, and here we find that the extent to which alcohol increases participants’ sensitivity to bodily states impacts their subjective drinking experiences. This was observed in relation to mood and light-headedness, but also on prospective alcohol expectancies. We posit that over successive alcohol experiences, changes in bodily states may feed into the development of alcohol expectancies that could in turn predict future drinking behaviors.