Compatible Donor and Recipient Pairs’ Perspectives on Participation in Kidney Paired Donation Programs: A Mixed-Methods Study

Background: Compatible pair participation in kidney paired donation (KPD) may increase the likelihood of finding suitable matches for all registered pairs. Retrospective studies have shown variable enthusiasm for participating in KPD in compatible pairs. Objective: The study objective was to gather potential living donor (PLD) and transplant candidate (TC) perspectives on compatible pair participation in KPD. Design: Surveys and qualitative interviews. Setting: Three transplant programs in Canada: Centre hospitalier de l’Université de Montréal in Montreal (Québec), Vancouver General Hospital, and St. Paul’s Hospital in Vancouver (British Columbia). Patients: Both PLDs and TCs undergoing evaluation for donation/transplantation between 2016 and 2018 at 3 transplant programs in Canada. Methods: Descriptive statistical analysis was performed for the results of the survey and thematic and content analysis method was used for the content of the qualitative interviews. Results: A total of 116 PLDs and 111 TCs completed surveys and an additional 18 PLDs and 17 TCs underwent semi-directed interviews. Of those surveyed, 61.2% of PLDs and 76.6% of TCs reported a willingness to participate in KPD as a compatible pair. The possibility of a more optimally matched kidney for the TC and policies ensuring prioritization of the TC for repeat transplantation in the event of early graft failure increased willingness to participate in KPD. Major concerns expressed during the interviews included the desire to retain the emotional bond of directed donation, the fear of chain breaks or donor reneging, delays in transplantation, and additional travel associated with participation in KPD. Limitation: The limitations of this study are that it was conducted in only 3 Canadian transplant programs and that the interviews and surveys were in French and in English. As a consequence, the results may not be reflective of the views of individuals not living in these 2 provinces and from ethnic minority populations. Conclusion: Most of the compatible PLDs and TCs surveyed were willing to participate in KPD. Ensuring timely transplantation and a more optimal match for TCs and offering a policy of reciprocity to ensure timely repeat transplantation for compatible recipients if their allograft fails post KPD transplant may further increase compatible pair participation in KPD.

P1730KIDNEY PAIRED DONATION IN SLOVAKIA - TOWARDS TO THE NATIONALLY COORDINATED PROGRAMME

Background and Aims AB0 and HLA incompatibility between donor and recipient is one of the possible reasons of the low rate of living kidney donation in Slovakia. Method We present a retrospective analysis of living donor kidney transplantations (LDKT) in Slovakia including kidney paired donations. Results During the period from 2015 to 2019 there were 823 kidney transplantations, 81 (9,8%) were from living donors. Kidney paired donations are performed since 2005. Altogether 8 two-way paired exchanges were done in 3 transplant centers. The first exchange between two centers was carried out in 2015. A majority of the involved pairs (81%) were married couples, one exchange was initiated by compatible pair. Surgical procedures were simultaneous, cold ischemia times were comparable to other LDKT (median 162 vs 182 minutes). Two recipients had early acute rejection, 3-year graft survival is 100%. There were no serious complications in donors. The participation in EU project ENCKEP (European Network for Collaboration on Kidney Exchange Programmes) has led to the creation of national registry of incompatible pairs in 2018 and the standardization of medical and legal processes of paired exchanges. Conclusion Above reported experience is adequate prerequisite for the launch of nationally coordinated programme and international cooperation.

Poisson Λ-brackets for Differential–Difference Equations

We introduce the notion of a multiplicative Poisson $\lambda$-bracket, which plays the same role in the theory of Hamiltonian differential–difference equations as the usual Poisson $\lambda$-bracket plays in the theory of Hamiltonian partial differential equations (PDE). We classify multiplicative Poisson $\lambda$-brackets in one difference variable up to order 5. As an example, we demonstrate how to apply the Lenard–Magri scheme to a compatible pair of multiplicative Poisson $\lambda$-brackets of order 1 and 2, to establish integrability of the Volterra chain.

NUMBER OF COMPATIBLE PAIR OF ACTIONS FOR FINITE CYCLIC GROUPS OF P-POWER ORDER

The compatible actions played an important role before determining the nonabelian tensor product of groups. Different compatible pair of actions gives a different nonabelian tensor product even for the same group. The aim of this paper is to determine the exact number of the compatible pair of actions for the finite cyclic groups of p-power order where p is an odd prime. By using the necessary and sufficient number theoretical conditions for a pair of the actions to be compatible with the actions that have p-power order, the exact number of the compatible pair of actions for the finite cyclic groups of p-power order has been determined and given as a main result in this paper.

Generalized Common Fixed Point Result in Banach Space

The aim of this paper is to establish a common fixed point theorem for weakly compatible pair of self mappings in Banach space which generalizes and improves various well known comparable results.