Exocrinous function of pancreas in Crohn’s disease patients

The functional state of pancreas in patients with the Crohn’s disease was studied. In feces of patients with CD, irritable colon syndrome, and healthy persons, the daily fat amount was determined by the van de Kamer’s method and fecal elastase-1 was determined using the immune-enzyme test with monoclonal antibodies (EIA system of BioServ Diagnostics, Elastase 1-ELISA, Germany). The fecal elstase-1 level in absolute and relative values in patients with CD decreases statistically confidently as the main disease becomes more severe.