Investigation of THz Absorptive Signatures in Opioids

We investigate the possibility of sensing opioid drugs, such as fentanyl, by their THz electromagnetic signatures. The methods include both computer modeling and experiments. Molecular dynamics simulations predict that fentanyl should display THz resonances, with several of them occurring below 1.0 THz; the lowest one is at around 0.337 THz (337 GHz). Spectroscopy measurements were conducted on oxycodone, which was used as a surrogate for fentanyl. They display vibrational absorption resonances between ∼1.4 and 1.6 THz.

Quantitative Vibrational Spectroscopy on Liquid Mixtures: Concentration Units Matter

Quantitative vibrational absorption spectroscopies rely on Beer’s law relating spectroscopic intensities in a linear fashion to chemical concentrations. To address and clarify contrasting results in the literature about the difference...

Efficient intersystem crossing in 2-aminopurine riboside probed by femtosecond time-resolved transient vibrational absorption spectroscopy

The photophysical dynamics of 2-aminopurine, a fluorescent analogue of the canonical nucleobase adenine, has been studied by femtosecond transient vibrational absorption spectroscopy.

Ultrafast dynamics of the ESIPT photoswitch N-(3-pyridinyl)-2-pyridinecarboxamide

A potential ESIPT photoswitch has been investigated by femtosecond time-resolved electronic and vibrational absorption spectroscopy.