The Use of UiO-Type MOFs in Vapour Phase Soai Reactions

We report a novel vapour phase procedure to perform the Soai reaction in an absolute asymmetric synthesis fashion: the substrate is confined in the pores of the UiO-type MOFs, and vapour phase reactions with Zn(i-Pr)₂ are performed in a sealed environment, Different MOFs lead to different outcomes in terms of enantiomeric excess, handedness of the product and reaction rate. This is one of the first examples of absolute asymmetric synthesis performed inside a MOF.

The Use of UiO-Type MOFs in Vapour Phase Soai Reactions

We report a novel vapour phase procedure to perform the Soai reaction in an absolute asymmetric synthesis fashion: the substrate is confined in the pores of the UiO-type MOFs, and vapour phase reactions with Zn(i-Pr)₂ are performed in a sealed environment, Different MOFs lead to different outcomes in terms of enantiomeric excess, handedness of the product and reaction rate. This is one of the first examples of absolute asymmetric synthesis performed inside a MOF.

Formation of enantioenriched alkanol with stochastic distribution of enantiomers in the absolute asymmetric synthesis under heterogeneous solid–vapor phase conditions

Absolute asymmetric synthesis under heterogeneous solid–vapor phase conditions in conjunction with asymmetric autocatalysis was achieved.

The Strecker reaction coupled to Viedma ripening: a simple route to highly hindered enantiomerically pure amino acids

We introduce a methodology based on a combination of the classical Strecker reaction, simple condensation and Viedma ripening, which allows absolute asymmetric synthesis of highly sterically hindered α-amino acids. As proof-of-principle, enantiomerically pure unnatural α-amino acids tert-leucine and α-(1-adamantyl)glycine have been obtained.

SINTESIS ABSOLUT ASIMETRIK BARU

ABSTRACT New absolute asymmetric syntheses have been found. Eugenol based-acetylenes monomers have been synthesized, corresponding three compounds and one unknown compound. Two compounds are crystal chiral (1 and 2) and one (3) not. Polymerization of chiral crystal and not were different although the structure is same. After recrystalization polymerization of 1 and 2 compare with 3 also different. This is one example of new absolute asymmetric synthesis. Keywords : New absolute asymmetric synthesis, eugenol, unknown compound, chiral crystal.