toxin extrusion Latest Research Papers

These proton:organic cation exchangers are predicted to have 13 TM segments [12] and are suggested to be responsible for excretion of many drugs in the liver and kidneys [1].

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Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.c21-00429 ◽

2021 ◽

Vol 69 (9) ◽

pp. 905-912

Author(s):

Susumu Shinya ◽

Kentaro Kawai ◽

Atsushi Tarui ◽

Yukiko Karuo ◽

Kazuyuki Sato ◽

...

Keyword(s):

Toxin Extrusion

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Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK‐7264), a P2X3 Receptor Antagonist

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.988 ◽

2021 ◽

Author(s):

Jesse C. Nussbaum ◽

Azher Hussain ◽

Bennett Ma ◽

K. Chris Min ◽

Raymond Evers ◽

...

Keyword(s):

Receptor Antagonist ◽

Potent Inhibitor ◽

P2x3 Receptor ◽

Toxin Extrusion

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Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters

Journal of Molecular Biology ◽

10.1016/j.jmb.2021.166959 ◽

2021 ◽

pp. 166959

Author(s):

Derek P. Claxton ◽

Kevin L. Jagessar ◽

Hassane S. Mchaourab

Keyword(s):

Alternating Access ◽

Toxin Extrusion

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Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

British Journal of Pharmacology ◽

10.1111/bph.15370 ◽

2021 ◽

Author(s):

Claudia Neul ◽

Ute Hofmann ◽

Elke Schaeffeler ◽

Stefan Winter ◽

Kathrin Klein ◽

...

Keyword(s):

Cytochrome P450 ◽

Organic Cation ◽

Organic Cation Transporters ◽

Cation Transporters ◽

Cyp 2D6 ◽

Toxin Extrusion

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Tamsulosin Alters the Pharmacokinetics of Metformin Via Inhibition of Renal Multidrug and Toxin Extrusion Protein 1 and Organic Cation Transporter 2 in Rats

SSRN Electronic Journal ◽

10.2139/ssrn.3969179 ◽

2021 ◽

Author(s):

Abdulaziz Ahmed A.Saad ◽

Fan zhang ◽

Moath Refata ◽

Eyad Abdulwhab H.Mohammed ◽

Mingkang Zhang ◽

...

Keyword(s):

Organic Cation ◽

Organic Cation Transporter ◽

Organic Cation Transporter 2 ◽

Toxin Extrusion

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Impact of direction of transport on the evaluation of inhibition potencies of multidrug and toxin extrusion protein 1 (MATE1) inhibitors

Drug Metabolism and Disposition ◽

10.1124/dmd.120.000136 ◽

2020 ◽

pp. DMD-AR-2020-000136

Author(s):

Asami Saito ◽

Naoki Ishiguro ◽

Masahito Takatani ◽

Bojan Bister ◽

Hiroyuki Kusuhara

Keyword(s):

Inhibition Potencies ◽

Toxin Extrusion

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Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2022 ◽

2020 ◽

Author(s):

Takeshi Miyake ◽

Emi Kimoto ◽

Lina Luo ◽

Sumathy Mathialagan ◽

Lauren M. Horlbogen ◽

...

Keyword(s):

Risk Assessment ◽

Drug Interactions ◽

Healthy Volunteers ◽

Toxin Extrusion

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Multidrug and Toxin Extrusion Protein 2

10.32388/usotuo ◽

2020 ◽

Author(s):

Keyword(s):

Toxin Extrusion

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toxin extrusion
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Amiloride is a suitable fluorescent substrate for the study of the drug transporter human multidrug and toxin extrusion 1 (MATE1)

SLC47 family of multidrug and toxin extrusion transporters in GtoPdb v.2021.3

Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)

Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK‐7264), a P2X3 Receptor Antagonist

Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters

Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Tamsulosin Alters the Pharmacokinetics of Metformin Via Inhibition of Renal Multidrug and Toxin Extrusion Protein 1 and Organic Cation Transporter 2 in Rats

Impact of direction of transport on the evaluation of inhibition potencies of multidrug and toxin extrusion protein 1 (MATE1) inhibitors

Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Multidrug and Toxin Extrusion Protein 2

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toxin extrusionRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

Amiloride is a suitable fluorescent substrate for the study of the drug transporter human multidrug and toxin extrusion 1 (MATE1)

SLC47 family of multidrug and toxin extrusion transporters in GtoPdb v.2021.3

Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)

Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK‐7264), a P2X3 Receptor Antagonist

Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters

Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Tamsulosin Alters the Pharmacokinetics of Metformin Via Inhibition of Renal Multidrug and Toxin Extrusion Protein 1 and Organic Cation Transporter 2 in Rats

Impact of direction of transport on the evaluation of inhibition potencies of multidrug and toxin extrusion protein 1 (MATE1) inhibitors

Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Multidrug and Toxin Extrusion Protein 2

toxin extrusion
Recently Published Documents