hepatocyte spheroid
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Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury

2021 ◽  
Author(s):  
Christopher A. Schofield ◽  
Tracy M. Walker ◽  
Maxine A. Taylor ◽  
Metul Patel ◽  
Denise F. Vlachou ◽  
...  
Keyword(s):  
Liver Injury ◽  
Three Dimensional ◽  
Human Hepatocyte ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Hepatocyte Spheroid ◽  
Primary Human Hepatocyte

scholarly journals Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies

2021 ◽  
Vol 110 (1) ◽  
pp. 422-431
Author(s):  
Kajsa P. Kanebratt ◽  
Annika Janefeldt ◽  
Liisa Vilén ◽  
Anna Vildhede ◽  
Kristin Samuelsson ◽  
...  
Keyword(s):  
Human Hepatocyte ◽  
Hepatocyte Spheroid ◽  
Primary Human Hepatocyte

Establishment of a primary human hepatocyte spheroid system for evaluating metabolic toxicity using dacarbazine under conditions of CYP1A2 induction

2020 ◽  
Vol 35 (2) ◽  
pp. 201-206
Author(s):  
Kenta Mizoi ◽  
Mayu Hosono ◽  
Hajime Kojima ◽  
Takuo Ogihara
Keyword(s):  
Human Hepatocyte ◽  
Hepatocyte Spheroid ◽  
Primary Human Hepatocyte

scholarly journals Characterisation of a functional rat hepatocyte spheroid model

2019 ◽  
Vol 55 ◽  
pp. 160-172 ◽  
Author(s):  
Jonathan A. Kyffin ◽  
Parveen Sharma ◽  
Joseph Leedale ◽  
Helen E. Colley ◽  
Craig Murdoch ◽  
...  
Keyword(s):  
Rat Hepatocyte ◽  
Hepatocyte Spheroid

Primary human hepatocyte spheroid generation and performance in different culture systems

2018 ◽  
Vol 295 ◽  
pp. S116
Author(s):  
S. Buesch ◽  
M. Bunger ◽  
J. Schroeder ◽  
M. Stosik
Keyword(s):  
Human Hepatocyte ◽  
Culture Systems ◽  
Hepatocyte Spheroid ◽  
Primary Human Hepatocyte ◽  
And Performance

Development of a primary human hepatocyte spheroid culture model for drug metabolism and disposition studies

2018 ◽  
Vol 33 (1) ◽  
pp. S69
Author(s):  
Kajsa P. Kanebratt ◽  
Annika Janefeldt ◽  
Alexandra Peric ◽  
Julia Jonsson ◽  
Linnea Johansson ◽  
...  
Keyword(s):  
Drug Metabolism ◽  
Human Hepatocyte ◽  
Spheroid Culture ◽  
Hepatocyte Spheroid ◽  
Primary Human Hepatocyte ◽  
Culture Model

scholarly journals Effect of amine content and chemistry on long-term, three-dimensional hepatocyte spheroid culture atop aminated elastin-like polypeptide coatings

2016 ◽  
Vol 105 (2) ◽  
pp. 377-388 ◽  
Author(s):  
C. Andrew Weeks ◽  
Bethany Aden ◽  
Junlin Zhang ◽  
Anisha Singh ◽  
Raymond D. Hickey ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Spheroid Culture ◽  
Hepatocyte Spheroid ◽  
Amine Content

Development of an automated, high-throughput hepatocyte spheroid screen for use within the pharmaceutical industry

2016 ◽  
Vol 258 ◽  
pp. S142
Author(s):  
D. Williams ◽  
A. Foster ◽  
C. Sefton ◽  
S. Regan ◽  
A. Woods ◽  
...  
Keyword(s):  
Pharmaceutical Industry ◽  
High Throughput ◽  
Hepatocyte Spheroid

scholarly journals Effect of charge content and chemistry on long-term, 3-D hepatocyte spheroid culture

2016 ◽  
Vol 4 ◽  
Author(s):  
Weeks C Andrew ◽  
Aden Bethany ◽  
Zhang Junlin ◽  
Kilbey S Michael ◽  
Janorkar Amol
Keyword(s):  
Spheroid Culture ◽  
Hepatocyte Spheroid

Hepatocyte spheroid culture on fibrous scaffolds with grafted functional ligands as an in vitro model for predicting drug metabolism and hepatotoxicity

2015 ◽  
Vol 28 ◽  
pp. 138-148 ◽  
Author(s):  
Shili Yan ◽  
Jiaojun Wei ◽  
Yaowen Liu ◽  
Hong Zhang ◽  
Jianmei Chen ◽  
...  
Keyword(s):  
Drug Metabolism ◽  
In Vitro Model ◽  
Spheroid Culture ◽  
Fibrous Scaffolds ◽  
Hepatocyte Spheroid ◽  
Vitro Model
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