Can Mozart Improve Weight Gain and Development of Feeding Skills in Premature Infants? A Randomized Trial

Objective The study aimed to assess in a prospective randomized study the effect of Mozart's music on time to regain birth weight (BW) and development of oral feeding skills in babies born between 280/7 and 316/7 weeks of gestation. Study Design Healthy premature infants born between 280/7 and 316/7 completed weeks of gestation were randomized within 3 days of birth to either music or no music exposure. Infants in the music group were exposed to Mozart's double piano sonata twice per day for 14 days. The primary outcome was time to regain birth weight. The secondary outcome was development of oral feeding skills as evaluated by a speech/language pathologist blinded to the intervention. We hypothesized that exposure to Mozart's double piano sonata would decrease time to regain BW and improve feeding skills. A total of 32 newborns were needed to detect a 3-day difference in time to regain BW. Results Forty infants were enrolled and randomized. There were no significant differences between the two groups regarding the time to regain BW (p = 0.181) and the time to achievement of full oral feeds (p = 0.809). Conclusion Exposure to Mozart's double piano sonata for 14 days after birth did not significantly improve time to regain BW or time to achieve full oral feedings in very premature infants. It is possible that Mozart's music has no effect or that the duration of music exposure was not sufficient to have a physiologic effect on growth and oral feeding skills. Key Points

Cosmetics vs Cosmeceuticals Why to Choose Cosmeceutials?

The global trend in the cosmetic industry towards developing ‘medicinally’ active cosmetics, and in the pharmaceutical industry towards ‘cosmetically’ oriented medicinal products. All cosmeceuticals claim to contain functional ingredients with either therapeutic, disease-fighting or healing properties. It provides external aesthetic benefits; the additional medicinal properties of cosmeceuticals are based on molecular structure, biological function relationships, and modes of action related to healing, anti-aging, free radical rampage reduction, dead epidermal cell exfoliation, and so on. In cosmeceuticals the importantance to know the interaction between skin and cosmeceuticals which could even be influenced by environmental fact. Online reviews and beauty blogs have created a community of peer reviewers that we encourage trust in Beauty Brand’s. The science of it all remains extremely crucial in making informed decisions for your skin. More than just Cosmetics, “Cosmeceuticals” is a term that every beauty junkie should learn more about this 2018. This study paper speaks about the science behind cosmeceuticals and how to make informed decisions when choosing beauty products. Today’s Cosmeceuticals are serving as a bridge between personal care products and pharmaceuticals; there is no regulatory category for Cosmeceuticals; hence this review tries to understand regulatory scenario as well the difference between drug and cosmetics is enlightened. The paper is an earnest endeavor to evaluate a Cosmeceutical product that claims a beneficial physiologic effect. This review paper is to give recent knowledge about the latest trend of cosmetic industry New challenges will also be presented to government regulatory agencies as more chemicals with true biological activity are invented and tested.