glycinamide ribonucleotide formyltransferase Recently Published Documents

Glycinamide Ribonucleotide Formyltransferase Inhibitor

10.32388/x37hbg ◽

2020 ◽

Author(s):

Keyword(s):

Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase

Biochemistry ◽

10.1021/acs.biochem.7b00092 ◽

2017 ◽

Vol 56 (7) ◽

pp. 1025-1025

Author(s):

Siobhan M. Deis ◽

Arpit Doshi ◽

Zhanjun Hou ◽

Larry H. Matherly ◽

Aleem Gangjee ◽

...

Keyword(s):

Enzymatic Analysis ◽

Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase

Biochemistry ◽

10.1021/acs.biochem.6b00412 ◽

2016 ◽

Vol 55 (32) ◽

pp. 4574-4582 ◽

Cited By ~ 5

Author(s):

Siobhan M. Deis ◽

Arpit Doshi ◽

Zhanjun Hou ◽

Larry H. Matherly ◽

Aleem Gangjee ◽

...

Keyword(s):

Enzymatic Analysis ◽

Novel 5-Substituted Pyrrolo[2,3-d]pyrimidines as Dual Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase and as Potential Antitumor Agents

10.1021/jm501787c ◽

2015 ◽

Vol 58 (3) ◽

pp. 1479-1493 ◽

Cited By ~ 14

Author(s):

Yiqiang Wang ◽

Shermaine Mitchell-Ryan ◽

Sudhir Raghavan ◽

Christina George ◽

Steven Orr ◽

...

Keyword(s):

Antitumor Agents ◽

Glycinamide Ribonucleotide Formyltransferase ◽

Dual Inhibitors ◽

Potential Antitumor

Discovery of 5-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity

10.1021/jm401328u ◽

2013 ◽

Vol 56 (24) ◽

pp. 10016-10032 ◽

Cited By ~ 22

Author(s):

Shermaine Mitchell-Ryan ◽

Yiqiang Wang ◽

Sudhir Raghavan ◽

Manasa Punaha Ravindra ◽

Eric Hales ◽

...

Keyword(s):

Antitumor Activity ◽

De Novo ◽

Ampk Activation ◽

Purine Nucleotide ◽

Nucleotide Biosynthesis ◽

Abstract 3823: 2-Methyl-6-substituted pyrrolo[2,3-d]pyrimidine classical antifolates as selective folate receptor substrates, glycinamide ribonucleotide formyltransferase inhibitors and antitumor agents

10.1158/1538-7445.am2012-3823 ◽

2012 ◽

Author(s):

Aleem Gangjee ◽

Sai Zhao ◽

Lei Wang ◽

Steven Orr ◽

Erika Etnyre ◽

...

Keyword(s):

Antitumor Agents ◽

Folate Receptor ◽

Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase

10.1021/jm200739e ◽

2011 ◽

Vol 54 (20) ◽

pp. 7150-7164 ◽

Cited By ~ 48

Author(s):

Lei Wang ◽

Sita Kugel Desmoulin ◽

Christina Cherian ◽

Lisa Polin ◽

Kathryn White ◽

...

Keyword(s):

Antitumor Activity ◽

Folate Receptor ◽

Reduced Folate Carrier ◽

Receptor Selectivity ◽

ChemInform Abstract: Inhibitors of Glycinamide Ribonucleotide Formyltransferase as Potential Cytotoxic Agents. Synthesis of 5-Deaza-5,6,7,8- tetrahydrohomofolic Acid, 5-Deaza-5,6,7,8-tetrahydroisohomofolic Acid, and 10-Formyl-5-deaza-5,6,7,8-tetrahydroiso

ChemInform ◽

10.1002/chin.199523233 ◽

2010 ◽

Vol 26 (23) ◽

pp. no-no

Author(s):

E. C. TAYLOR ◽

C. YOON ◽

J. M. HAMBY

Keyword(s):

Cytotoxic Agents ◽

Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity

10.1021/jm8003366 ◽

2008 ◽

Vol 51 (16) ◽

pp. 5052-5063 ◽

Cited By ~ 46

Author(s):

Yijun Deng ◽

Yiqiang Wang ◽

Christina Cherian ◽

Zhanjun Hou ◽

Steven A. Buck ◽

...

Keyword(s):

Antitumor Activity ◽

Folate Receptor ◽

Glycinamide Ribonucleotide Formyltransferase ◽

High Affinity