irradiated allografts
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2014 ◽  
Vol 38 (9) ◽  
pp. 1913-1921 ◽  
Author(s):  
Philippe Hernigou ◽  
Jacques Pariat ◽  
Steffen Queinnec ◽  
Yasuhiro Homma ◽  
Charles Henri Flouzat Lachaniette ◽  
...  


2007 ◽  
Vol 35 (10) ◽  
pp. 1653-1658 ◽  
Author(s):  
Matthew Rappe ◽  
MaryBeth Horodyski ◽  
Keith Meister ◽  
Peter A. Indelicato

Background Many studies suggest that gamma irradiation decreases allograft strength in a dose-dependent manner. No study has demonstrated that this decrease in strength translates into higher clinical failures. Hypothesis Irradiation of allograft tissue will lead to higher early clinical failure in anterior cruciate ligament (ACL) reconstruction. Study Design Cohort study; Level of evidence, 3. Methods Medical records were reviewed for 90 consecutive patients who had received Achilles allograft reconstruction for unilateral primary ACL injuries at one institution between July 2001 and June 2002. One half of patients received nonirradiated Achilles allograft and the other half received irradiated Achilles allograft at a dose range of 2.0 to 2.5 Mrad. The ACL allograft reconstructions were performed using the same surgical technique. The rehabilitation program was identical for both groups. All clinical failures were recorded. Results At least 6 months’ follow-up was available on 42 subjects in the nonirradiated group and 33 subjects in the irradiated group. A significant difference was noted in early failure rates between the groups (P < .01). The nonirradiated group had 1 in 42 (2.4%) catastrophic failure. In the irradiated group, 11 of 33 (33%) Achilles tendon grafts failed. Conclusions Less than satisfactory results led the senior authors to discontinue the use of irradiated allografts in ACL surgery. Continued research into alternatives to gamma irradiation is needed.



2003 ◽  
Vol 4 (2-4) ◽  
pp. 203-211 ◽  
Author(s):  
A. Lobo Gajiwala


2003 ◽  
Vol 4 (2-4) ◽  
pp. 119-123 ◽  
Author(s):  
V. Trivedi ◽  
A. Lobo Gajiwala ◽  
S. Deshpande


2003 ◽  
Vol 4 (2-4) ◽  
pp. 125-132 ◽  
Author(s):  
A. Lobo Gajiwala ◽  
M. Agarwal ◽  
A. Puri ◽  
C. D'Lima ◽  
A. Duggal


2000 ◽  
Vol 375 ◽  
pp. 214-217 ◽  
Author(s):  
Steven A. Lietman ◽  
William W. Tomford ◽  
Mark C. Gebhardt ◽  
Dempsey S. Springfield ◽  
Henry J. Mankin


1995 ◽  
Vol 57 (4) ◽  
pp. 591-594
Author(s):  
Masahiro YASUDA ◽  
Yasuho TAURA ◽  
Satoshi UNE ◽  
Munekazu NAKAICHI ◽  
Sanenori NAKAMA


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