Nephrologic abnormalities in neonatal asphyxia at Cipto Mangunkusumo Hospital, Jakarta

Introduction Neonatal asphyxia is still the leading cause of highmorbidity and mortality in developed countries, as well as in devel-oping countries including Indonesia. As a response to asphyxia,renal hypoxia occurs which is initially temporary, but if persisting,can cause permanent damage to the cortex and medulla.Objective The purpose of this study was to determine thenephrologic abnormalities in neonatal asphyxia at CiptoMangunkusumo Hospital.Methods This was a cross sectional descriptive study conductedin the Division of Neonatology, Cipto Mangunkusumo Hospital fromAugust until November 2002. Neonates with congenital malforma-tion were excluded.Results The study showed that the incidence of nephrologic ab-normalities in neonatal asphyxia based on Apgar scores at 1, 5,and 10 minutes were 65/100, 26/33, and 5/6, respectively. The riskof nephrologic abnormalities was not statistically different in se-vere asphyxia compared to moderate asphyxia. Severe asphyxiaat 1 minute Apgar scores was correlated with the occurrence ofoliguria.Conclusion In asphyxiated newborn, it is very important to inves-tigate the possibility of nephrologic abnormalities

Congenital malformations in the neonatal unit of Arifin Achmad Hospital, Pekanbaru: occurrence and trends

Background Congenital malformations are a global and continualissue, contributing to neonatal mortality. The incidence andprevalence, as well as distribution of congenital malformationsvary among countries.Objective To determine the 'prevalence, distribution, and trendsin congenital malformations which are important to develop plansto cope Mth the problem.Methods We reviewed all cases of congenital malformationsadmitted to the Neonatal Unit, Department of Child Health,Arifin Ahmad Hospital from 2008 to 2010. Data were collectedfrom medical records. Diagnoses of congenital malformationswere established by history-taking, physical examination,and specific laboratory tests. Trends in the distribution ofcongenital malformation types, as well as clinical outcomes werehighlighted.Results During the study period there were 2,317 infants admit-ted to the Neonatal Unit, 724 in 2008, 772 in 2009, and 821 in2010. Most patients were referred by other hospitals, at the ageof 0-3 days. Most patients had normal birth weight and were de-livered vaginally. Of the 2,317 infants, 302 were diagnosed withcongenital malformations; the most common congenital malfor-mations were of the digestive tract. The distribution of anomalytypes was relatively constant over time, but the proportion ofpatients Mth congenital malformations discharged alive increasedin the latter two years of the 3-year period studied.Conclusion Most infants in our study had congenital malforma-tions involving the gastrointestinal tract. Distribution trendswere constant over time. Further efforts should be made to bettermanage future cases. [Paediatr lndones. 2012;52:284,8].