Intramolecular Chalcogenylation of Isooxazolines Mediated by PhICl2 and Diorganyl Disulfides or Diselenides

Reactive organosulfenyl chlorides (ArSCl) or selenenyl chlorides (ArSeCl), generated in situ from the reaction of PhICl2 with diorganyl disulfides or diselenides, enable the intramolecular oxidative cyclization/chalcogenylation of β,γ-unsaturated oximes, leading to the formation of a series of chalcogenylated isooxazolines in good to excellent yield.

Visible-Light Induced and Copper-Catalyzed Oxidative Cyclization of Substituted o-Aminophenylacetylene for the Synthesis of Quinoline and Indole Derivatives

Herein we report on the development of a mild and efficient intramolecular oxidative cyclization reaction of substituted aromatic enamines and C(sp3)-H bond adjacent to nitrogen with alkynes or alkenes, leading...

A convenient approach for the preparation of imidazo[1,2-a]-fused bicyclic frameworks via IBX/NIS promoted oxidative annulation

IBX/NIS induced intramolecular oxidative cyclization of Mannich substrates is reported, affording highly diverse imidazo[1,2-a]-pyridines, -pyrimidines and -pyrazines in up to 93% isolated yield. In addition, one-pot procedure is also represented.