Chiral Fluorescence Recognition by Anthracene Fluorescent Dyes ⊂ Water-Soluble Pillar[5]arene Containing Phosphonic Acid Group (PWP[5])

Chirality plays a pivotal role in drugs, agrochmeicals and food additives et al. The enantiomers of a chiral molecule often show huge difference in bioactivity, metabolism, and toxicity et al. thereby, the recognition of chiral molecules shows an increasingly important priority, and has become an important focus and frontier in medicine, biochemistry and other fields. In this paper, a novel method for chiral fluorescence recognition based on anthracene fluorescent dyes(AD) ⊂ water-soluble pillar[5] arene containing phosphonic acid group(PWP[5]) is developed. The AD as guest molecule can complex with PWP[5] to form 1:1 AD ⊂ PWP[5] assembly, and this assembly can be further used as a fluorescent probe to identify D/L-phenylalanine and D/L-phenylalaninol by fluorescent titration. The fluorescence intensity of the assembly was significantly reduced for D-phenylalanine and D-phenylalaninol, while L-phenylalanine or L-phenylalaninol was added to AD ⊂ PWP[5] assembly, the fluorescence intensity of the assembly almost unchanged. Hence, the chiral recognition based on assembly between the achiral fused ring fluorescent dye and achiral PWP[5] was developed.

Quantitative Analysis Of Fˉ Ion Recognition By A New Chemosensor from Flavon Group

A new chemosensor S8 compound from the flavon group that has been successfully synthesized. Test its ability as a chemosensor for F- anion, providing positive results that it can recognize F- anion with response to an increase in fluorescent solution. Titration of S8 solution in DMSO solvents was carried out with F- anion at various concentrations and then measurements were made on fluorometry instruments. The fluorescent titration emission spectrum shows that the S8-Fˉ host-guest interaction quantitatively in the form of LOD and kass. LOD and Kass values are 6.43 × 10ˉ4 M and 2 × 106 Mˉ1, respectively.