cytotoxic steroids
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2020 ◽  
Vol 56 (6) ◽  
pp. 1094-1099
Author(s):  
Zhengxiang Xia ◽  
Lihua Lu ◽  
Lin Li


2020 ◽  
Vol 56 (1) ◽  
pp. 173-176
Author(s):  
Ying-Ying Wang ◽  
Shu-Ning Zheng ◽  
Ting Tian ◽  
Zhen-Zhen Zheng ◽  
Lie-Feng Ma ◽  
...  


2019 ◽  
Vol 5 (2) ◽  
pp. 143-148
Author(s):  
Dewa Gede Katja ◽  
Desi Harneti ◽  
Tri Mayanti ◽  
Nurlelasari Nurlelasari ◽  
Rani Maharani ◽  
...  

In the course of our continuing search for anticancer compounds from Chisocheton species, three steroids, stigmast-5-en-3β-ol (1), stigmast-5-en-3β-ol-3-O-β-D-glucopyranoside (2) and stigmast-5,22-dien-3β-ol-3-O-β-D-glucopyranoside (3), were obtained from the stembark of Chisocheton celebicus. The structures of compound 1-3 were identified with spectroscopic data including IR, 1D-NMR, 2D-NMR and TOF-MS, as well as by comparing with those spectral data previously. Compounds 1-3, were evaluated for their cytotoxic effects against P-388 murine leukemia cells and displayed the cytotoxicity activity with IC50 values of 12.45 ± 0.050, 52.27 ± 0.031 and 62.52 ± 0.076 µg/mL, respectively.



Steroids ◽  
2018 ◽  
Vol 138 ◽  
pp. 57-63 ◽  
Author(s):  
Nguyen Hoai Nam ◽  
Ninh Thi Ngoc ◽  
Tran Thi Hong Hanh ◽  
Nguyen Xuan Cuong ◽  
Nguyen Van Thanh ◽  
...  
Keyword(s):  


Steroids ◽  
2018 ◽  
Vol 136 ◽  
pp. 17-21 ◽  
Author(s):  
Song-Wei Li ◽  
Wen-Ting Chen ◽  
Li-Gong Yao ◽  
Yue-Wei Guo


Author(s):  
Kindi Farabi ◽  
◽  
Desi Harneti ◽  
Nurlelasari Nurlelasari ◽  
Rani Maharani ◽  
...  
Keyword(s):  


Molekul ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. 1 ◽  
Author(s):  
Dewa Gede Katja ◽  
Kindi Farabi ◽  
Nurlelasari Nurlelasari ◽  
Desi Harneti ◽  
Euis Julaeha ◽  
...  

Three cytotoxic steroids, stigmasterol (1), stigmast-5-en-3b-ol (2) and b-sitosterol-3-O-acetate (3) were isolated from the stem bark of Chisocheton cumingianus. The chemical structures of those compounds were identified based on spectroscopic data and by comparison with those data previously reported. All of the compounds isolated were evaluated for their cytotoxic effects against P-388 murine leukemia cells in vitro. Compounds 1-3 showed cytotoxicity activity against P-388 murine leukemia cells with IC50values of 12.4, 60.8, and ˃ 100 mg/mL, respectively.



2017 ◽  
Vol 65 (3) ◽  
pp. 300-305 ◽  
Author(s):  
Ninh Thi Ngoc ◽  
Pham Thi Mai Huong ◽  
Nguyen Van Thanh ◽  
Nguyen Thi Phuong Chi ◽  
Nguyen Hai Dang ◽  
...  


2017 ◽  
Vol 65 (6) ◽  
pp. 593-597 ◽  
Author(s):  
Ninh Thi Ngoc ◽  
Tran Thi Hong Hanh ◽  
Nguyen Van Thanh ◽  
Do Thi Thao ◽  
Nguyen Xuan Cuong ◽  
...  


Steroids ◽  
2014 ◽  
Vol 86 ◽  
pp. 26-31 ◽  
Author(s):  
Hui-Jiao Yan ◽  
Jun-Song Wang ◽  
Ling-Yi Kong


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