Clinical cases of the formation of outer retinal tubulations after aflibercept injections in exudative and disciform age-related macular degeneration

Outer retinal tubulation (ORT) is a common finding in optical coherence tomography, which is usually associated with age-related macular degeneration. It is not clear are ORT appear as a sign of a degenerative process in the outer retinal layers or a way of photoreceptors survival. There are no data on the dynamics of ORT associated with angiogenesis inhibitors injections. This paper presents two clinical cases of dynamic observation of tubulation formation in age-related macular degeneration in the disciform scar stage and in the exudation stage after Aflibercept injections based on optical coherence tomography – angiography and scanning laser ophthalmoscopy. Key words: оuter retinal tabs, age-related macular degeneration, angiogenesis inhibitors.