Assessment of Temperature and Specific Humidity Inversions and Their Relationships in Three Global Reanalysis Products over the Arctic Ocean

Characteristics of temperature inversions (TIs) and specific humidity inversions (SHIs) and their relationships in three of the latest global reanalyses—the European Centre for Medium-Range Weather Forecasts Interim Reanalysis (ERA-I), the Japanese 55-year Reanalysis (JRA-55), and the ERA5—are assessed against in situ radiosonde (RS) measurements from two expeditions over the Arctic Ocean. All reanalyses tend to detect many fewer TI and SHI occurrences, together with much less common multiple TIs and SHIs per profile than are seen in the RS data in summer 2008, winter 2015, and spring 2015. The reanalyses generally depict well the relationships among TI characteristics seen in RS data, except for the TIs below 400 m in summer, as well as above 1000 m in summer and winter. The depth is simulated worst by the reanalyses among the SHI characteristics, which may result from its sensitivity to the uncertainties in specific humidity in the reanalyses. The strongest TI per profile in RS data exhibits more robust dependency on surface conditions than the strongest SHI per profile, and the former is better presented by the reanalyses than the latter. Furthermore, all reanalyses have difficulties simulating the relationships between TIs and SHIs, together with the correlations between the simultaneous inversions. The accuracy and vertical resolution in the reanalyses are both important to properly capture occurrence and characteristics of the Arctic inversions. In general, ERA5 performs better than ERA-I and JRA-55 in depicting the relationships among the TIs. However, the representation of SHIs is more challenging than TIs in all reanalyses over the Arctic Ocean.

Defining and surveying key populations at risk of HIV infection: Towards a unified approach to eligibility criteria for respondent-driven sampling HIV biobehavioral surveys

Substantial resources are invested in human immunodeficiency virus biobehavioral surveys using respondent-driven sampling for measuring progress towards the UNAIDS 90–90–90 goals and to obtain other essential data on key populations. Survey data are used to meet country needs as well those of development partners, whose data needs may sometimes diverge. Surveys using differing eligibility criteria impede comparisons across surveys. With scant literature and guidelines on how to approach eligibility criteria, diverse criteria are used within and across countries. We conducted a review of peer-reviewed human immunodeficiency virus respondent-driven sampling biobehavioral survey literature published through December 2013. We describe eligibility criteria of 137 articles representing 214 surveys. Reporting on age, risk behavior, and reference period of risk behavior was nearly universal; however, reporting on gender, geography, and language was less common. Multiple definitions were used for each criterion, making comparisons challenging. We provide a framework for how to approach defining eligibility to improve consistency and comparability across surveys.

Multiple Suture Synostosis and Increased Intracranial Pressure following Repair of Single Suture, Nonsyndromal Craniosynostosis

Objective Increased intracranial pressure, frequently associated with closure of multiple cranial sutures, has been reported to occur in 36% of cases following correction of syndromal craniosynostosis. Although much less common, multiple suture closure may occur following repair of single suture, non-syndromal craniosynostosis and we present cases that concern two such children. Results Two children with nonsyndromal craniosynostosis, one metopic and one left-coronal, underwent fronto-orbital advancement at age 3 months. At age 19 months and at age 5 years, respectively, both patients re-presented with headaches, decrease in head circumference percentile, and acceptable cosmetic outcome. Both had computerized tomographic evidence of multiple closed cranial sutures and increased intracranial pressure (ICP) (determined by monitoring). Both patients improved following a cranial expansion procedure. Conclusion Delayed closure of multiple sutures and resultant increased ICP may occur following correction of nonsyndromal, single suture craniosynos-tosis. This may be more likely when the initial suture is contiguous with the facial sutures. Children should be followed for many years following cranio-synostosis repair with cranial, neurologic, and possibly funduscopic examinations as well as head circumference measurements to detect delayed closure of cranial sutures.