Defining and surveying key populations at risk of HIV infection: Towards a unified approach to eligibility criteria for respondent-driven sampling HIV biobehavioral surveys

2018 ◽  
Vol 29 (9) ◽  
pp. 895-903 ◽  
Author(s):  
Avi J Hakim ◽  
Lisa G Johnston ◽  
Samantha Dittrich ◽  
Dimitri Prybylski ◽  
Janet Burnett ◽  
...  

Substantial resources are invested in human immunodeficiency virus biobehavioral surveys using respondent-driven sampling for measuring progress towards the UNAIDS 90–90–90 goals and to obtain other essential data on key populations. Survey data are used to meet country needs as well those of development partners, whose data needs may sometimes diverge. Surveys using differing eligibility criteria impede comparisons across surveys. With scant literature and guidelines on how to approach eligibility criteria, diverse criteria are used within and across countries. We conducted a review of peer-reviewed human immunodeficiency virus respondent-driven sampling biobehavioral survey literature published through December 2013. We describe eligibility criteria of 137 articles representing 214 surveys. Reporting on age, risk behavior, and reference period of risk behavior was nearly universal; however, reporting on gender, geography, and language was less common. Multiple definitions were used for each criterion, making comparisons challenging. We provide a framework for how to approach defining eligibility to improve consistency and comparability across surveys.

2019 ◽  
Vol 69 (9) ◽  
pp. 1613-1620 ◽  
Author(s):  
Alexander Breskin ◽  
Daniel Westreich ◽  
Christopher B Hurt ◽  
Stephen R Cole ◽  
Michael G Hudgens ◽  
...  

Abstract Background The cost of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) prompted many payers to restrict treatment to patients who met non–evidence-based criteria. These restrictions have implications for survival of people with HCV, especially for people with human immunodeficiency virus (HIV)/HCV coinfection who are at high risk for liver disease progression. The goal of this work was to estimate the effects of DAA access policies on 10-year all-cause mortality among people with HIV. Methods The study population included 3056 adults with HIV in the Women’s Interagency HIV Study and Multicenter AIDS Cohort Study from 1 October 1994 through 30 September 2015. We used the parametric g-formula to estimate 10-year all-cause mortality under DAA access policies that included treating (i) all people with HCV; (ii) only people with suppressed HIV; (iii) only people with severe fibrosis; and (iv) only people with HIV suppression and severe fibrosis. Results The 10-year risk difference of treating all coinfected persons with DAAs compared with no treatment was –3.7% (95% confidence interval [CI], –9.1% to .6%). Treating only those with suppressed HIV and severe fibrosis yielded a risk difference of –1.1% (95% CI, –2.8% to .6%), with 51% (95% CI, 38%–59%) of coinfected persons receiving DAAs. Treating a random selection of 51% of coinfected persons at baseline decreased the risk by 1.9% (95% CI, –4.7% to .3%). Conclusions Restrictive DAA access policies may decrease survival compared to treating similar proportions of people with HIV/HCV coinfection with DAAs at random. These findings suggest that lives could be saved by thoughtfully revising access policies.


2012 ◽  
Vol 20 (3) ◽  
pp. 536-542 ◽  
Author(s):  
Helisamara Mota Guedes ◽  
Luciana Oliveira Costa Cabral ◽  
Maria Verônica de Barros Costa ◽  
Alex Ferreira dos Reis ◽  
Simone Gomes Pereira ◽  
...  

This study aimed to verify risk behavior for infection with the Human Immunodeficiency Virus in people who attended motels. This is a cross-sectional study conducted in two motels in two municipalities in the state of Minas Gerais, Brazil, with a sample of 308 randomly selected individuals, aged between 18 and 60 years. Bivariate (chi-square and t test for independent samples) and multivariate (logistic regression) statistical tests were performed. A total of 45.8% of the participants reported not having used a condom during the last vaginal sexual intercourse, 48.4% did not use a condom during the last oral sex, while 26.3% reported not having used a condom in the last anal intercourse. Having a steady partner was the strongest predictor of not using condoms. Probable beliefs regarding loyalty involved in a stable relationship may be contributing to the failure to use condoms during intercourse, increasing the risk of HIV infection.


2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Charlene Flash ◽  
Xiaoying Yu ◽  
Syundai Johnson ◽  
Oluwatobi Adegboyega ◽  
Kenneth Mayer ◽  
...  

2016 ◽  
Vol 170 (2) ◽  
pp. 125 ◽  
Author(s):  
Patrick A. Wilson ◽  
Shoshana Y. Kahana ◽  
Maria Isabel Fernandez ◽  
Gary W. Harper ◽  
Kenneth Mayer ◽  
...  

2008 ◽  
Vol 35 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Richard A. Rawson ◽  
Rachel Gonzales ◽  
Valerie Pearce ◽  
Alfonso Ang ◽  
Patricia Marinelli-Casey ◽  
...  

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