Respons Imun Terhadap Infeksi Bakteri

Guna menjaga integritas dan identitas individu diperlukan suatu sistem pertahanan tubuhyang adekuat. Mekanisme imunitas terhadap antigen yang berbahaya meliputi pertahananfisik dan kimiawi, simbiosis dengan bakteri flora normal, innate immunity serta imunitasspesifik yang didapat, terdiri dari imunitas humoral serta imunitas selular (cell mediatedimmunity). Antigen Major Histo Compatibility (MHC) berperan pada presentasi antigenoleh makrofag. Respons imun terhadap bakteri meliputi bakteri ekstra seluler dan intraselular. Pada infeksi bakteri yang berat dapat terjadi kelelahan respons imun (exchaustion),dalam keadaan ini pemberian terapi penunjang imunoglobulin intra vena dapatdipertimbangkan.

Effect of the Immunological Antigenicity of the Allogeneic Tendons on Tendon Grafting

The authors have investigated the immunological rejection responses against allogeneic tendon tissue using two strains of inbred rats. A complement dependent cytotoxicity test and an absorbing test were used. The results indicate that the rat tendon tissue contained major histo-compatibility antigens, that this was largely present in tendon cell components, and that collagen showed little or no response.