Methods in Molecular Biology - Structure-Based Drug Discovery
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15

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Published By Humana Press

9781617795190, 9781617795206

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The Utility of Structural Biology in Drug Discovery

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_1 ◽

2011 ◽

pp. 1-27 ◽

Author(s):

Leslie W. Tari

Keyword(s):

Drug Discovery ◽

Structural Biology

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The Use of Molecular Graphics in Structure-Based Drug Design

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_6 ◽

2011 ◽

pp. 143-159 ◽

Author(s):

Paul Emsley ◽

Judit É. Debreczeni

Keyword(s):

Drug Design ◽

Molecular Graphics ◽

Structure Based Drug Design

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Crystallographic Fragment Screening

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_7 ◽

2011 ◽

pp. 161-177 ◽

Author(s):

John Badger

Keyword(s):

Fragment Screening

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Structure-Based Drug Design on Membrane Protein Targets: Human Integral Membrane Protein 5-Lipoxygenase-Activating Protein

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_12 ◽

2011 ◽

pp. 267-290 ◽

Author(s):

Andrew D. Ferguson

Keyword(s):

Drug Design ◽

Membrane Protein ◽

Integral Membrane Protein ◽

Structure Based Drug Design ◽

Protein Targets

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Leveraging SBDD in Protein Therapeutic Development: Antibody Engineering

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_14 ◽

2011 ◽

pp. 321-349 ◽

Author(s):

Gary L. Gilliland ◽

Jinquan Luo ◽

Omid Vafa ◽

Juan Carlos Almagro

Keyword(s):

Antibody Engineering ◽

Protein Therapeutic ◽

Therapeutic Development

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Accounting for Solvent in Structure-Based Drug Design

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_11 ◽

2011 ◽

pp. 251-266 ◽

Author(s):

Leslie W. Tari

Keyword(s):

Drug Design ◽

Structure Based Drug Design

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Genetic Construct Design and Recombinant Protein Expression for Structural Biology

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_2 ◽

2011 ◽

pp. 29-47 ◽

Author(s):

Suzanne C. Edavettal ◽

Michael J. Hunter ◽

Ronald V. Swanson

Keyword(s):

Recombinant Protein ◽

Protein Expression ◽

Structural Biology ◽

Recombinant Protein Expression ◽

Genetic Construct

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Protein Crystallization for Structure-Based Drug Design

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_4 ◽

2011 ◽

pp. 67-91 ◽

Author(s):

Isaac D. Hoffman

Keyword(s):

Drug Design ◽

Protein Crystallization ◽

Structure Based Drug Design

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Purification of Proteins for Crystallographic Applications

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_3 ◽

2011 ◽

pp. 49-65

Author(s):

Daniel C. Bensen

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Chemical Informatics: Using Molecular Shape Descriptors in Structure-Based Drug Design

Methods in Molecular Biology - Structure-Based Drug Discovery ◽

10.1007/978-1-61779-520-6_10 ◽

2011 ◽

pp. 235-250 ◽

Author(s):

Andy Jennings

Keyword(s):

Drug Design ◽

Molecular Shape ◽

Shape Descriptors ◽

Structure Based Drug Design ◽

Chemical Informatics

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