Methods in Enzymology - Fragment-Based Drug Design - Tools, Practical Approaches, and Examples
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Predicting the Success of Fragment Screening by X-Ray Crystallography

2011 ◽  
pp. 91-114 ◽  
Author(s):  
Douglas R. Davies ◽  
Darren W. Begley ◽  
Robert C. Hartley ◽  
Bart L. Staker ◽  
Lance J. Stewart
Keyword(s):  
X Ray ◽  
X Ray Crystallography ◽  
Fragment Screening

scholarly journals Fragment Screening of Infectious Disease Targets in a Structural Genomics Environment

2011 ◽  
pp. 533-556 ◽  
Author(s):  
Darren W. Begley ◽  
Douglas R. Davies ◽  
Robert C. Hartley ◽  
Thomas E. Edwards ◽  
Bart L. Staker ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Structural Genomics ◽  
Fragment Screening

Key Factors for Successful Generation of Protein–Fragment Structures

2011 ◽  
pp. 61-89 ◽  
Author(s):  
Jark Böttcher ◽  
Anja Jestel ◽  
Reiner Kiefersauer ◽  
Stephan Krapp ◽  
Susanna Nagel ◽  
...  
Keyword(s):  
Key Factors ◽  
Protein Fragment

Lead Generation and Examples

2011 ◽  
pp. 383-419 ◽  
Author(s):  
Masaya Orita ◽  
Kazuki Ohno ◽  
Masaichi Warizaya ◽  
Yasushi Amano ◽  
Tatsuya Niimi
Keyword(s):  
Lead Generation
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