Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design
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12

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Published By Springer Berlin Heidelberg

9783642550409, 9783642550416

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Physical Properties in Drug Design

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2013_35 ◽

2014 ◽

pp. 1-68 ◽

Author(s):

Robert J. Young

Keyword(s):

Drug Design ◽

Physical Properties

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Erratum to: Drug-Induced Phospholipidosis: Prediction, Detection, and Mitigation Strategies

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2014_73 ◽

2014 ◽

pp. 387-387

Author(s):

Umesh M. Hanumegowda ◽

Alicia Regueiro-Ren

Keyword(s):

Mitigation Strategies ◽

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Erratum to: Drug Discovery vs hERG

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2014_72 ◽

2014 ◽

pp. 385-385

Author(s):

Derek J. Leishman ◽

Zoran Rankovic

Keyword(s):

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Erratum to: The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2014_74 ◽

2014 ◽

pp. 389-390

Author(s):

Nicholas A. Meanwell

Keyword(s):

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Erratum to: Improving Solubility via Structural Modification

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2014_71 ◽

2014 ◽

pp. 383-383

Author(s):

Michael A. Walker

Keyword(s):

Structural Modification

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Drug Discovery vs hERG

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2014_38 ◽

2014 ◽

pp. 225-259 ◽

Author(s):

Derek J Leishman ◽

Zoran Rankovic

Keyword(s):

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Avoiding PXR and CAR Activation and CYP3A4 Enzyme Induction

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2013_24 ◽

2013 ◽

pp. 159-190 ◽

Author(s):

Michael W. Sinz

Keyword(s):

Enzyme Induction ◽

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Improving Solubility via Structural Modification

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2013_32 ◽

2013 ◽

pp. 69-106 ◽

Author(s):

Michael A. Walker

Keyword(s):

Structural Modification

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Strategies for Minimisation of the Cholestatic Liver Injury Liability Posed by Drug-Induced Bile Salt Export Pump (BSEP) Inhibition

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2013_30 ◽

2013 ◽

pp. 191-223

Author(s):

J. Gerry Kenna ◽

Simone H. Stahl ◽

Tobias Noeske

Keyword(s):

Liver Injury ◽

Bile Salt ◽

Bile Salt Export Pump ◽

Drug Induced ◽

Cholestatic Liver Injury

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The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems

Topics in Medicinal Chemistry - Tactics in Contemporary Drug Design ◽

10.1007/7355_2013_29 ◽

2013 ◽

pp. 283-381 ◽

Author(s):

Nicholas A. Meanwell

Keyword(s):

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