Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems

The Role of Ligand Rebinding and Facilitated Dissociation on the Characterization of Dissociation Rates by Surface Plasmon Resonance (SPR) and Benchmarking Performance Metrics

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_11 ◽

2021 ◽

pp. 237-253

Author(s):

Aykut Erbaş ◽

Fatih Inci

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Performance Metrics ◽

Ligand Rebinding ◽

Benchmarking Performance

Download Full-text

Beyond the Michaelis–Menten: Bayesian Inference for Enzyme Kinetic Analysis

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_3 ◽

2021 ◽

pp. 47-64

Author(s):

Hyukpyo Hong ◽

Boseung Choi ◽

Jae Kyoung Kim

Keyword(s):

Bayesian Inference ◽

Kinetic Analysis ◽

Enzyme Kinetic

Download Full-text

Current Approaches of Building Mechanistic Pharmacodynamic Drug–Target Binding Models

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_1 ◽

2021 ◽

pp. 1-17

Author(s):

Jingyi Liang ◽

Vi Ngoc-Nha Tran ◽

Colin Hemez ◽

Pia Abel zur Wiesch

Keyword(s):

Drug Target ◽

Binding Models ◽

Target Binding

Download Full-text

Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug Discovery

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_15 ◽

2021 ◽

pp. 325-334

Author(s):

Tom Dixon ◽

Samuel D. Lotz ◽

Alex Dickson

Keyword(s):

Drug Discovery ◽

Ligand Binding

Download Full-text

Computational Alanine Scanning Reveals Common Features of TCR/pMHC Recognition in HLA-DQ8-Associated Celiac Disease

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_13 ◽

2021 ◽

pp. 293-312

Author(s):

Linqiong Qiu ◽

Jianing Song ◽

John Z. H. Zhang

Keyword(s):

Celiac Disease ◽

Alanine Scanning ◽

Common Features ◽

Computational Alanine Scanning

Download Full-text

Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_5 ◽

2021 ◽

pp. 91-115

Author(s):

Andrea Degasperi ◽

Lan K. Nguyen ◽

Dirk Fey ◽

Boris N. Kholodenko

Keyword(s):

Optimization Algorithms ◽

Scaling Factor ◽

Data Driven

Download Full-text

Computational Methods for Structure-Based Drug Design Through System Biology

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_9 ◽

2021 ◽

pp. 161-174

Author(s):

Aman Chandra Kaushik ◽

Shakti Sahi ◽

Dong-Qing Wei

Keyword(s):

Drug Design ◽

Computational Methods ◽

System Biology ◽

Structure Based Drug Design

Download Full-text

Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM:MM Approaches

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_10 ◽

2021 ◽

pp. 175-236

Author(s):

Michał Glanowski ◽

Sangita Kachhap ◽

Tomasz Borowski ◽

Maciej Szaleniec

Keyword(s):

Reaction Kinetics ◽

Enzyme Reaction ◽

Model Setup

Download Full-text

Umbrella Sampling-Based Method to Compute Ligand-Binding Affinity

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_14 ◽

2021 ◽

pp. 313-323

Author(s):

Son Tung Ngo ◽

Minh Quan Pham

Keyword(s):

Ligand Binding ◽

Binding Affinity ◽

Umbrella Sampling

Download Full-text

Dynamic Optimization Approach to Estimate Kinetic Parameters of Monod-Based Microalgae Growth Models

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems ◽

10.1007/978-1-0716-1767-0_6 ◽

2021 ◽

pp. 117-140

Author(s):

Siti S. Jamaian ◽

Fathul H. Zulkifli ◽

Kim S. Ling

Keyword(s):

Kinetic Parameters ◽

Dynamic Optimization ◽

Growth Models ◽

Optimization Approach ◽

Microalgae Growth

Download Full-text

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems
Latest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer US

The Role of Ligand Rebinding and Facilitated Dissociation on the Characterization of Dissociation Rates by Surface Plasmon Resonance (SPR) and Benchmarking Performance Metrics

Beyond the Michaelis–Menten: Bayesian Inference for Enzyme Kinetic Analysis

Current Approaches of Building Mechanistic Pharmacodynamic Drug–Target Binding Models

Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug Discovery

Computational Alanine Scanning Reveals Common Features of TCR/pMHC Recognition in HLA-DQ8-Associated Celiac Disease

Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI

Computational Methods for Structure-Based Drug Design Through System Biology

Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM:MM Approaches

Umbrella Sampling-Based Method to Compute Ligand-Binding Affinity

Dynamic Optimization Approach to Estimate Kinetic Parameters of Monod-Based Microalgae Growth Models

Export Citation Format

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological SystemsLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer US

The Role of Ligand Rebinding and Facilitated Dissociation on the Characterization of Dissociation Rates by Surface Plasmon Resonance (SPR) and Benchmarking Performance Metrics

Beyond the Michaelis–Menten: Bayesian Inference for Enzyme Kinetic Analysis

Current Approaches of Building Mechanistic Pharmacodynamic Drug–Target Binding Models

Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug Discovery

Computational Alanine Scanning Reveals Common Features of TCR/pMHC Recognition in HLA-DQ8-Associated Celiac Disease

Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI

Computational Methods for Structure-Based Drug Design Through System Biology

Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM:MM Approaches

Umbrella Sampling-Based Method to Compute Ligand-Binding Affinity

Dynamic Optimization Approach to Estimate Kinetic Parameters of Monod-Based Microalgae Growth Models

Methods in Molecular Biology - Computational Methods for Estimating the Kinetic Parameters of Biological Systems
Latest Publications