Cost-effectiveness of Noninvasive Diagnostic Aids in Suspected Pulmonary Embolism

1997 ◽  
Vol 157 (20) ◽  
pp. 2309 ◽  
Author(s):  
Arnaud Perrier
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism

The cost-effectiveness of diagnostic strategies in patients with suspected pulmonary embolism

1996 ◽  
Vol 5 (4) ◽  
pp. 307-318 ◽  
Author(s):  
Bowine C. Michel ◽  
Rob J. Seerden ◽  
Frans F. H. Rutten ◽  
Edwin J. R. van Beek ◽  
Harry R. Büller
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
The Cost

scholarly journals Correspondence

2013 ◽  
Vol 12 (1) ◽  
pp. 57-58
Author(s):  
Bryan Renton ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism ◽  
Acute Medicine ◽  
Nice Guidance ◽  
Venous Thromboembolic ◽  
Recent Edition

Dear Sir, I read with interest the article by Langford et al in the recent edition of Acute Medicine, summarising the NICE guidance for the management of venous thromboembolic diseases.1 This highlights the recommendation that CTPA should be the investigation of choice for patients with suspected pulmonary embolism (PE), in view of its clinical and cost effectiveness.

A Comparative Analysis of D-Dimer Assays in Patients with Clinically Suspected Pulmonary Embolism

1993 ◽  
Vol 70 (03) ◽  
pp. 408-413 ◽  
Author(s):  
Edwin J R van Beek ◽  
Bram van den Ende ◽  
René J Berckmans ◽  
Yvonne T van der Heide ◽  
Dees P M Brandjes ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Comparative Analysis ◽  
High Probability ◽  
Pulmonary Emboli ◽  
Plasma Samples ◽  
Suspected Pulmonary Embolism ◽  
Lung Scan ◽  
D Dimer

SummaryTo avoid angiography in patients with clinically suspected pulmonary embolism and non-diagnostic lung scan results, the use of D-dimer has been advocated. We assessed plasma samples of 151 consecutive patients with clinically suspected pulmonary embolism. Lung scan results were: normal (43), high probability (48) and non-diagnostic (60; angiography performed in 43; 12 pulmonary emboli). Reproducibility, cut-off values, specificity, and percentage of patients in whom angiography could be avoided (with sensitivity 100%) were determined for two latex and four ELISA assays.The latex methods (cut-off 500 μg/1) agreed with corresponding ELISA tests in 83% (15% normal latex, abnormal ELISA) and 81% (7% normal latex, abnormal ELISA). ELISA methods showed considerable within- (2–17%) and between-assay Variation (12–26%). Cut-off values were 25 μg/l (Behring), 50 μg/l (Agen), 300 μg/l (Stago) and 550 μg/l (Organon). Specificity was 14–38%; in 4–15% of patients angiography could be avoided.We conclude that latex D-dimer assays appear not useful, whereas ELISA methods may be of limited value in the exclusion of pulmonary embolism.

Sign in / Sign up

Export Citation Format

Share Document