scholarly journals High Levels of Serotonin Transporter Occupancy With Low-Dose Clomipramine in Comparative Occupancy Study With Fluvoxamine Using Positron Emission Tomography

2003 ◽  
Vol 60 (4) ◽  
pp. 386 ◽  
Author(s):  
Tetsuya Suhara ◽  
Akihiro Takano ◽  
Yasuhiko Sudo ◽  
Tetsuya Ichimiya ◽  
Makoto Inoue ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Serotonin Transporter ◽  
Low Dose ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Positron Emission Tomography Quantification of Serotonin Transporter in Suicide Attempters with Major Depressive Disorder

2013 ◽  
Vol 74 (4) ◽  
pp. 287-295 ◽  
Author(s):  
Jeffrey M. Miller ◽  
Natalie Hesselgrave ◽  
R. Todd Ogden ◽  
Gregory M. Sullivan ◽  
Maria A. Oquendo ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Serotonin Transporter ◽  
Emission Tomography ◽  
Major Depressive ◽  
Suicide Attempters ◽  
Positron Emission

Positron emission tomography imaging of the serotonin transporter in the pig brain using [11C](+)-McN5652 and S-([18F]fluoromethyl)-(+)-McN5652

Synapse ◽  
2002 ◽  
Vol 47 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Peter Brust ◽  
J�rg Zessin ◽  
Hiroto Kuwabara ◽  
Beate Pawelke ◽  
Marion Kretzschmar ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Serotonin Transporter ◽  
Positron Emission Tomography Imaging ◽  
Emission Tomography ◽  
Tomography Imaging ◽  
Pig Brain ◽  
Positron Emission

scholarly journals Spared Caudal Brainstem SERT Binding in Early Parkinson's Disease

2007 ◽  
Vol 28 (3) ◽  
pp. 441-444 ◽  
Author(s):  
Roger L Albin ◽  
Robert A Koeppe ◽  
Nicolaas I Bohnen ◽  
Kristine Wernette ◽  
Michael A Kilbourn ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Positron Emission Tomography ◽  
Parkinson's Disease ◽  
Serotonin Transporter ◽  
Emission Tomography ◽  
Serotoninergic Neurons ◽  
Positron Emission ◽  
Brainstem Nuclei ◽  
Early Parkinson’S Disease ◽  
Normal Controls

Postmortem data indicate loss of serotoninergic neurons in Parkinson's disease (PD). We used the serotonin transporter (SERT) radioligand 3-amino-4-(2-dimethylaminomethyl-phenylsulfaryl)-benzonitril (DASB) and positron emission tomography to examine SERT distribution and changes in early PD subjects. We studied five PD subjects (H&Y 1 to 2.5) and eight normal controls. There is reduced SERT binding in PD. The magnitude of DASB binding reductions was greater in the forebrain than in the brainstem regions. There was no asymmetry of diminished SERT binding. DASB binding in the medulla was relatively spared, inconsistent with the description of early prominent pathologic study in these caudal brainstem nuclei.

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