Diagnostic Performance of Computed Tomography Angiography in Peripheral Arterial Disease

Background Patients with substantially impaired kidney function and peripheral arterial disease (PAD) underwent comparative CO2-based depiction of the pelvic arteries (PAs). Purpose To evaluate the feasibility and diagnostic performance of CO2-based C-arm computed tomography (CACT) and compare its depiction of PAs with CO2-digital subtraction angiography (DSA). Material and Methods Fifteen patients (10 men, mean age 70 ± 11 years) with PAD received CO2-DSA and CO2-CACT of the PAs, depicted from the aorta to femoral arteries. These were divided into nine segments (135 in total) and graded by two independent readers for image quality (IQ; 1 = sufficient, 2 = minimal impairments, 3 = insufficient, 4 = outside field of view) and subsequent stenosis grading (SG; grade 1: normal to grade 4: occlusion), under exclusion of all segments with insufficient IQ. Inter-observer and inter-modality agreement calculation and subsequent consensus reading were performed and correlated to a standard of reference (StOR), representing a modality consensus. Results Of 135 segments, 117 showed sufficient IQ, excluding 18 segments (10 CACT, 8 DSA). Inter-observer agreement for IQ and consecutive SG demonstrated good to excellent agreement: IQDSA: κ = 0.83, IQCACT: κ = 0.76; StenosisDSA: κ = 0.71, StenosisCACT: κ = 0.84. Inter-modality agreement for SG lay at κ = 0.76 and κ = 0.65, respectively. More stenoses could be detected by CACT, and analysis of pooled consensus values of SG in CACTcons versus StOR showed an excellent agreement (κ = 0.96) that proved considerably higher than the moderate agreement between consensus values in DSAcons versus StOR (κ = 0.43). Conclusion CO2-CACT proved feasible, and has the potential to optimize angiographic work-up of PAD in patients with contraindications for other contrast media.

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Multidetector (64+) Computed Tomography Angiography of the Lower Limb in Symptomatic Peripheral Arterial Disease

Journal of Computer Assisted Tomography ◽

10.1097/rct.0000000000000494 ◽

2017 ◽

Vol 41 (2) ◽

pp. 327-333 ◽

Cited By ~ 4

Author(s):

Jeremy C. Lim ◽

Dinesh Ranatunga ◽

Andrew Owen ◽

Tim Spelman ◽

Michael Galea ◽

...

Keyword(s):

Computed Tomography ◽

Peripheral Arterial Disease ◽

Computed Tomography Angiography ◽

Lower Limb ◽

Arterial Disease ◽

Peripheral Arterial

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Computed Tomography Angiography Evaluation of Peripheral Arterial Disease and Correlation with Colour Doppler

Asian Journal of Medical Radiological Research ◽

10.47009/ajmrr.2020.8.2.12 ◽

2020 ◽

Vol 8 (2) ◽

pp. 73-79

Author(s):

M. Balaji Vara Prasad ◽

Srinadh Boppana ◽

Mounika Reddy ◽

Nainika Juvvadi ◽

Rajeshwari ◽

...

Keyword(s):

Computed Tomography ◽

Peripheral Arterial Disease ◽

Computed Tomography Angiography ◽

Vascular System ◽

Early Stage ◽

Signs And Symptoms ◽

Arterial Disease ◽

Colour Doppler ◽

Peripheral Arterial ◽

Sensitivity Specificity

Background: Peripheral Arterial Disease Is a Major Problem Among the Population of Those 55 Years and Older. MDCT is a Non-Invasive Method of Visualization of Vascular System. It Affords More Widespread Vascular Screening, Allowing Diagnosis to be Made at an Early Stage. The objective is to Assess the Role of Multidetector Computed Tomography Angiography in Peripheral Arterial Disease of Lower Extremities. Subjects & Methods: A Prospective Study of 35 Patients with Signs and Symptoms of PVD, Were Subjected to Colour Doppler Ultrasonography and MDCT Examination Between a Period of 1st August 2018 to 31st May 2019. Results: Our Study Shows a Very Good Sensitivity, Specificity, PPV, NPV and Accuracy of Doppler in Assessing the Soft Plaque (82%, 100%, 100%, 97%, 97% Respectively) & in Evaluation of Stenosis Like <50% Stenosis (100%, 99%, 85%, 100% & 99% Respectively), 50-99% Stenosis (100%, 99%, 96%. 100% & 99.8% Respectively), & Occlusion (84%, 100%. 100%, 98% & 98% Respectively). The Only Parameter Which Showed Poor Result Was in Evaluation of Calcified Plaque. Conclusion: Our Study Shows that Both Colour Doppler & MDCT Can Be Complimentary in Lower Limb Arterial Disease Evaluation.

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