scholarly journals Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors

JAMA Oncology ◽  
2022 ◽  
Author(s):  
◽  
Michelle Ghert ◽  
Patricia Schneider ◽  
Victoria Giglio ◽  
Paula McKay ◽  
...  
The Knee ◽  
2018 ◽  
Vol 25 (5) ◽  
pp. 952-958
Author(s):  
Fangzhou He ◽  
Chuanzhen Hu ◽  
Yuhui Shen ◽  
Qiyuan Bao ◽  
Junxiang Wen ◽  
...  

Sarcoma ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Koichi Ogura ◽  
Shimpei Miyamoto ◽  
Minoru Sakuraba ◽  
Tomohiro Fujiwara ◽  
Hirokazu Chuman ◽  
...  

Introduction. Although several intercalary reconstructions after resection of a lower extremity malignant bone tumor are reported, there are no optimal methods which can provide a long-term reconstruction with fewest complications. We present the outcome of reconstruction using a devitalized autograft and a vascularized fibula graft composite.Materials and Methods.We conducted a retrospective review of 11 patients (7 males, 4 females; median age 27 years) undergoing reconstruction using a devitalized autograft (pasteurization (n=6), deep freezing (n=5)) and a vascularized fibula graft composite for lower extremity malignant bone tumors (femur (n=10), tibia (n=1)).Results. The mean period required for callus formation and bone union was 4.4 months and 9.9 months, respectively. Four postoperative complications occurred in 3 patients: 2 infections (1 pasteurized autograft, 1 frozen autograft) and 1 fracture and 1 implant failure (both in pasteurized autografts). Graft removal was required in 2 patients with infections. The mean MSTS score was 81% at last follow-up.Conclusions.Although some complications were noted in early cases involving a pasteurized autograft, our novel method involving a combination of a frozen autograft with a vascularized fibula graft and rigid fixation with a locking plate may offer better outcomes than previously reported allografts or devitalized autografts.


Cancer ◽  
2003 ◽  
Vol 97 (10) ◽  
pp. 2554-2564 ◽  
Author(s):  
Rajaram Nagarajan ◽  
Joseph P. Neglia ◽  
Denis R. Clohisy ◽  
Yutaka Yasui ◽  
Mark Greenberg ◽  
...  

2019 ◽  
Vol 8 (3) ◽  
pp. 291-296 ◽  
Author(s):  
Shoko Katsumoto ◽  
Mitsue Maru ◽  
Tsukasa Yonemoto ◽  
Rumi Maeda ◽  
Keisuke Ae ◽  
...  

2021 ◽  
Vol 2 (2) ◽  
pp. 4-8
Author(s):  
Sagar Tontanahal ◽  
Gahukamble Abhay Deodas ◽  
Deeptiman James ◽  
Anand Kurian ◽  
Thomas Palocaren

Background: The management of malignant bone tumors in children has come a long way in the past few decades. The transition from amputation to limb salvage has been made possible due to the rapid development in the diagnosis and the oncological management of these malignant tumors. However, there exist significant reservations regarding endoprosthetic reconstruction in children. Material and methods: A mini-review was conducted of articles detailing the use of prosthetic reconstruction following tumor resection in children. The data regarding complications and functional outcomes following surgery were collected and presented. Results: The studies reviewed reported a 5-year survival rate between 60 – 70 %. Uniform across the studies was the need for multiple surgeries when endoprosthesis was used for limb reconstruction, ranging between 2.8 – 3.5 surgeries. The most common complication noted across the studies was related to soft tissue problems such as joint instability followed by structural failure of the prosthesis. Infections were noted with a frequency of 10 – 15 %. Studies showed successful management of limb length discrepancy with expandible prosthesis. Musculoskeletal Tumor Society (MSTS) score used to evaluate the functional outcome showed satisfactory outcomes. Conclusion: Limb salvage surgery, with recent advances in technique and prosthesis design, is an attractive option in children with extremity malignant bone tumors. In recent time, endoprosthetic reconstruction of extremities have yielded good functional results and are well accepted by the child and the parents. The purpose of this mini-review is to shed some light on the use of endoprosthetic reconstruction in children following tumor resection with its potential benefits and drawbacks.


2002 ◽  
Vol 19 (2) ◽  
pp. 62-62
Author(s):  
Amy Kenagy ◽  
Julie Casey ◽  
Kayley Weinstein
Keyword(s):  

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