Polymeric Micelles for the Delivery of Poorly Soluble Drugs

2013 ◽  
pp. 411-476 ◽  
Author(s):  
Swati Biswas ◽  
Onkar S. Vaze ◽  
Sara Movassaghian ◽  
Vladimir P. Torchilin
Keyword(s):  
Polymeric Micelles ◽  
Poorly Soluble Drugs ◽  
Poorly Soluble

Polymeric Micelles as Novel Carriers for Poorly Soluble Drugs— Review

2015 ◽  
Vol 15 (6) ◽  
pp. 4009-4018 ◽  
Author(s):  
B. Pavan Kumar Reddy ◽  
Hemant K. S. Yadav ◽  
Dattatri K. Nagesha ◽  
Abhay Raizaday ◽  
Abdul Karim
Keyword(s):  
Polymeric Micelles ◽  
Poorly Soluble Drugs ◽  
Poorly Soluble

Polymeric micelles in porous and nanotubular implants as a new system for extended delivery of poorly soluble drugs

2011 ◽  
Vol 21 (20) ◽  
pp. 7082 ◽  
Author(s):  
Moom Sinn Aw ◽  
Spomenka Simovic ◽  
Jonas Addai-Mensah ◽  
Dusan Losic
Keyword(s):  
Polymeric Micelles ◽  
Poorly Soluble Drugs ◽  
Poorly Soluble ◽  
New System

Technological Advancements in Oral Films

2019 ◽  
Vol 9 (01) ◽  
pp. 15-20
Author(s):  
B Pandey ◽  
A B Khan
Keyword(s):  
3D Printing ◽  
Historical Background ◽  
Poorly Soluble Drugs ◽  
Modern Approach ◽  
Poorly Soluble ◽  
Critical Process Parameters ◽  
Biopharmaceutical Properties ◽  
Oral Films ◽  
Hot Melt ◽  
Modern Technologies

The aim of the review was to explore the necessity, advantages and different techniques of oral films for enhancing solubility of poorly soluble drugs with an emphasis on the newer, state-of the art technologies, such as 3D printing and hot-melt extrusion (HME). The historical background of oral films is presented along with the regularly used techniques. The modern approach of quality-by-design (QbD) is unravelled, identifying appropriate critical process parameters (CPP) and applied to oral films. A section is devoted modern technologies such as 3D printing and HME of oral films. Oral films are innovative formulations by which poorly soluble drugs have been founds to give positive results in enhancing their solubility and dissolution characteristics. With modern sophisticated techniques, precise mass production of oral films has been given a thrust. Oral films have better patient compliance, improved biopharmaceutical properties, improved efficacy, and better safety. By applying QbD and implementation of modern technologies the newer generation of oral films are yielding promising results

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