Drug Metabolite Identification with High-resolution Mass Spectrometry

Drug Metabolite ◽

High Resolution Mass ◽

Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry

Journal of Mass Spectrometry ◽

10.1002/jms.1610 ◽

2009 ◽

Vol 44 (7) ◽

pp. 999-1016 ◽

Cited By ~ 183

Author(s):

Haiying Zhang ◽

Donglu Zhang ◽

Kenneth Ray ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Mass Defect ◽

Filter Technique ◽

Drug Metabolite ◽

High Resolution Mass ◽

Mass Defect Filter ◽

High-Resolution Mass Spectrometry and Drug Metabolite Identification

Mass Spectrometry in Drug Metabolism and Disposition ◽

10.1002/9780470929278.ch13 ◽

2011 ◽

pp. 407-448 ◽

Cited By ~ 5

Author(s):

Russell J. Mortishire-Smith ◽

Haiying Zhang ◽

Kevin P. Bateman

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Drug Metabolite ◽

High Resolution Mass ◽

Interspecies comparison of plasma metabolism and sample stabilization for quantitative bioanalyses: application to (R)-CE3F4 in preclinical development, including metabolite identification by high-resolution mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2021.122943 ◽

2021 ◽

pp. 122943

Author(s):

Balthazar Toussaint ◽

Hervé Hillaireau ◽

Emmanuel Jaccoulet ◽

Catherine Cailleau ◽

Pauline Legrand ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Preclinical Development ◽

Interspecies Comparison ◽

High Resolution Mass ◽

4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry

Forensic Toxicology ◽

10.1007/s11419-015-0287-4 ◽

2015 ◽

Vol 34 (1) ◽

pp. 61-75 ◽

Cited By ~ 29

Author(s):

Kayla N. Ellefsen ◽

Ariane Wohlfarth ◽

Madeleine J. Swortwood ◽

Xingxing Diao ◽

Marta Concheiro ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

In Silico ◽

Human Hepatocyte ◽

Metabolic Stability ◽

In Silico Prediction ◽

High Resolution Mass ◽

Metabolite identification and profile of endosulfan sulfate in three human liver preparations using liquid chromatography-high resolution mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2020.121996 ◽

2020 ◽

Vol 1140 ◽

pp. 121996

Author(s):

Hwa-Kyung Lee ◽

Tae Yeon Kong ◽

Won-Gu Choi ◽

Ju-Hyun Kim ◽

Yongho Shin ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

High Resolution ◽

Human Liver ◽

Endosulfan Sulfate ◽

High Resolution Mass ◽

Update on metabolism of abemaciclib: In silico , in vitro , and in vivo metabolite identification and characterization using high resolution mass spectrometry

Drug Testing and Analysis ◽

10.1002/dta.2725 ◽

2020 ◽

Vol 12 (3) ◽

pp. 331-342 ◽

Cited By ~ 2

Author(s):

Disha Thakkar ◽

Abhijeet S. Kate

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

In Silico ◽

High Resolution Mass ◽

Identification And Characterization ◽

Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation

Metabolomics ◽

10.1007/s11306-016-1064-z ◽

2016 ◽

Vol 12 (7) ◽

Cited By ~ 13

Author(s):

Justin J. J. van der Hooft ◽

Sandosh Padmanabhan ◽

Karl E. V. Burgess ◽

Michael P. Barrett

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Antihypertensive Drug ◽

Molecular Networking ◽

Drug Metabolite ◽

High Resolution Mass ◽

Mass Spectrometry Fragmentation ◽

Metabolite Screening ◽

Development of a Liquid Chromatography–High Resolution Mass Spectrometry Metabolomics Method with High Specificity for Metabolite Identification Using All Ion Fragmentation Acquisition

Analytical Chemistry ◽

10.1021/acs.analchem.7b00925 ◽

2017 ◽

Vol 89 (15) ◽

pp. 7933-7942 ◽

Cited By ~ 54

Author(s):

Shama Naz ◽

Hector Gallart-Ayala ◽

Stacey N. Reinke ◽

Caroline Mathon ◽

Richard Blankley ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

High Resolution ◽

High Specificity ◽

Ion Fragmentation ◽

High Resolution Mass ◽

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis - Comprehensive Analytical Chemistry ◽

High-Resolution Mass Spectrometry in Metabolite Identification

10.1016/bs.coac.2016.01.004 ◽

2016 ◽

pp. 199-229 ◽

Cited By ~ 2

Author(s):

M.K. Ladumor ◽

S. Tiwari ◽

A. Patil ◽

K. Bhavsar ◽

S. Jhajra ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass ◽

Drug Metabolite Profiling and Identification by High-resolution Mass Spectrometry

Journal of Biological Chemistry ◽

10.1074/jbc.r110.200055 ◽

2011 ◽

Vol 286 (29) ◽

pp. 25419-25425 ◽

Cited By ~ 128

Author(s):

Mingshe Zhu ◽

Haiying Zhang ◽

W. Griffith Humphreys

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Metabolite Profiling ◽

Drug Metabolite ◽

High Resolution Mass ◽