Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, and Pure Red Cell Aplasia

2009 ◽  
pp. 189-196
Author(s):  
Shivani Srivastava ◽  
Richard W. Childs
Keyword(s):  
Aplastic Anemia ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Red Cell Aplasia

Anemia: Production Defects Generally Associated with Marrow Aplasia or Replacement

2017 ◽  
Author(s):  
Nancy Berliner ◽  
John M Gansner
Keyword(s):  
Bone Marrow ◽  
Differential Diagnosis ◽  
Aplastic Anemia ◽  
Blood Smear ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Normal Bone Marrow ◽  
Normal Bone ◽  
Red Cell Aplasia

This review focuses on anemia resulting from production defects generally associated with marrow aplasia or replacement. The definition, epidemiology, etiology, pathogenesis, diagnosis, differential diagnosis, management, complications, and prognosis of the following production defects are discussed: Acquired aplastic anemia and acquired pure red cell aplasia. Figures depict a leukoerythroblastic blood smear, a biopsy comparing normal bone marrow and bone marrow showing almost complete aplasia, and a marrow smear. A table lists the causes of aplastic anemia. This review contains 3 figures; 1 table; 108 references.

A trial of immunotherapy in aplastic anemia and pure red cell aplasia

1983 ◽  
Vol 1 (2) ◽  
pp. 95-103 ◽  
Author(s):  
Neal S. Young ◽  
Harvey G. Klein ◽  
Patricia Griffith ◽  
Arthur W. Nienhuis
Keyword(s):  
Aplastic Anemia ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Red Cell Aplasia

Trend and treatment patterns of aplastic anemia in Korea, pure red cell aplasia and myelodysplastic syndrome in Korea: a nation-wide analysis

2017 ◽  
Vol 106 (4) ◽  
pp. 500-507
Author(s):  
Yunsuk Choi ◽  
Jae-Cheol Jo ◽  
Hee-jeong Jeon ◽  
Dong Wook Kim ◽  
Myung Hee Chang ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Aplastic Anemia ◽  
Pure Red Cell Aplasia ◽  
Treatment Patterns ◽  
Red Cell ◽  
Red Cell Aplasia

scholarly journals VI. Pathophysiology and Management of Aplastic Anemia and Pure Red Cell Aplasia

2015 ◽  
Vol 104 (7) ◽  
pp. 1405-1413
Author(s):  
Makoto Hirokawa ◽  
Naohito Fujishima ◽  
Ayumi Omokawa ◽  
Shigeharu Ueki
Keyword(s):  
Aplastic Anemia ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Red Cell Aplasia

Experience with Ciclosporin (CyA) in the Management of Pure Red-Cell Aplasia (PRCA) and Aplastic Anemia (AA)

1985 ◽  
pp. 261-264 ◽  
Author(s):  
Thomas H. Tötterman ◽  
A. Killander ◽  
A. Kreuger ◽  
G. Gustafsson ◽  
J. Nisell ◽  
...  
Keyword(s):  
Aplastic Anemia ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Red Cell Aplasia

scholarly journals Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Sumit Dahal ◽  
Eliza Sharma ◽  
Suyash Dahal ◽  
Binav Shrestha ◽  
Bikash Bhattarai
Keyword(s):  
Aplastic Anemia ◽  
Diagnostic Procedures ◽  
Pure Red Cell Aplasia ◽  
Red Cell ◽  
Early Presentation ◽  
Erythroid Precursor ◽  
Red Cell Aplasia ◽  
History Of ◽  
Intravenous Steroids ◽  
Acquired Amegakaryocytic Thrombocytopenia

Association of thymoma with myasthenia gravis, pure red cell aplasia, and aplastic anemia is well documented. However, thymoma complicated by acquired amegakaryocytic thrombocytopenia (AAMT) is rarely reported. Here, we present a case of a 60-year-old male with past medical history of recurrent invasive thymoma who presented with cough and blood in sputum. He was found to have severe normocytic normochromic anemia and thrombocytopenia that did not improve with intravenous steroids or multiple transfusions of red cells and platelets. Subsequent bone marrow biopsy showed severely depleted megakaryocytes and erythroid precursor cells with relative myeloid hyperplasia suggestive of amegakaryocytic thrombocytopenia and red cell aplasia. He was started on oral cyclosporine but subsequently developed leukopenia and refused any further treatment or diagnostic procedures and left the hospital against medical advice. AAMT, thus, may be a very early presentation of impending aplastic anemia, and treating physicians need to be aware of this entity.

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