scholarly journals Evaluation of radiophotoluminescent glass dosimeter response for therapeutic spot scanning proton beam: suggestion of linear energy transfer‐based correction

2021 ◽  
Author(s):  
Junya Nagata ◽  
Keisuke Yasui ◽  
Chihiro Omachi ◽  
Toshito Toshiyuki ◽  
Hidetoshi Shimizu ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer ◽  
Spot Scanning ◽  
Glass Dosimeter

The Change in the Linear Energy Transfer of a Clinical Proton Beam in the Presence of Gold Nanoparticles

BIOPHYSICS ◽  
2020 ◽  
Vol 65 (4) ◽  
pp. 541-547
Author(s):  
A. V. Belousov ◽  
V. N. Morozov ◽  
G. A. Krusanov ◽  
A. N. Moiseev ◽  
A. S. Davydov ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer

Direct Response to Proton Beam Linear Energy Transfer (LET) in a Novel Polymer Gel Dosimeter Formulation

2012 ◽  
Vol 11 (5) ◽  
pp. 441-445 ◽  
Author(s):  
O. Lopatiuk-Tirpak ◽  
Z. Su ◽  
Z. Li ◽  
O. A. Zeidan ◽  
S. L. Meeks ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer ◽  
Polymer Gel ◽  
Direct Response ◽  
Gel Dosimeter ◽  
Polymer Gel Dosimeter

scholarly journals Relative Biological Effect/Linear Energy Transfer in Proton Beam Therapy: A Primer

2019 ◽  
Vol 31 (12) ◽  
pp. 809-812 ◽  
Author(s):  
S.L. Gulliford ◽  
K.M. Prise
Keyword(s):  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer ◽  
Biological Effect ◽  
Proton Beam Therapy

scholarly journals Biological dose and complication probabilities for the rectum and bladder based on linear energy transfer distributions in spot scanning proton therapy of prostate cancer

2017 ◽  
Vol 56 (11) ◽  
pp. 1413-1419 ◽  
Author(s):  
Jesper Pedersen ◽  
Jørgen B. B. Petersen ◽  
Camilla H. Stokkevåg ◽  
Kristian S. Ytre-Hauge ◽  
Stella Flampouri ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Energy Transfer ◽  
Proton Therapy ◽  
Linear Energy Transfer ◽  
Spot Scanning ◽  
Biological Dose

scholarly journals A Novel Linear Energy Transfer Integrated Spot-Scanning Proton Arc Therapy Algorithm: Feasibility Study and Clinical Potential

2020 ◽  
Vol 108 (3) ◽  
pp. S187
Author(s):  
X. Li ◽  
X. Ding ◽  
W. Zheng ◽  
G. Liu ◽  
G. Janssens ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Feasibility Study ◽  
Linear Energy Transfer ◽  
Therapy Algorithm ◽  
Spot Scanning ◽  
Arc Therapy ◽  
Clinical Potential

Linear energy transfer dependence of a normoxic polymer gel dosimeter investigated using proton beam absorbed dose measurements

2004 ◽  
Vol 49 (17) ◽  
pp. 3847-3855 ◽  
Author(s):  
Helen Gustavsson ◽  
Sven Å J Bäck ◽  
Joakim Medin ◽  
Erik Grusell ◽  
Lars E Olsson
Keyword(s):  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer ◽  
Absorbed Dose ◽  
Polymer Gel ◽  
Gel Dosimeter ◽  
Polymer Gel Dosimeter ◽  
Dose Measurements

scholarly journals Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Xiaoqiang Li ◽  
Xuanfeng Ding ◽  
Weili Zheng ◽  
Gang Liu ◽  
Guillaume Janssens ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Organs At Risk ◽  
Substantial Improvement ◽  
Intensity Modulated Proton Therapy ◽  
Spot Scanning ◽  
Similar Dose ◽  
Arc Therapy ◽  
Clinical Benefits ◽  
Delivery Efficiency

PurposeTo integrate dose-averaged linear energy transfer (LETd) into spot-scanning proton arc therapy (SPArc) optimization and to explore its feasibility and potential clinical benefits.MethodsAn open-source proton planning platform (OpenREGGUI) has been modified to incorporate LETd into optimization for both SPArc and multi-beam intensity-modulated proton therapy (IMPT) treatment planning. SPArc and multi-beam IMPT plans with different beam configurations for a prostate patient were generated to investigate the feasibility of LETd-based optimization using SPArc in terms of spatial LETd distribution and plan delivery efficiency. One liver and one brain case were studied to further evaluate the advantages of SPArc over multi-beam IMPT.ResultsWith similar dose distributions, the efficacy of spatially optimizing LETd distributions improves with increasing number of beams. Compared with multi-beam IMPT plans, SPArc plans show substantial improvement in LETd distributions while maintaining similar delivery efficiency. Specifically, for the liver case, the average LETd in the GTV was increased by 124% for the SPArc plan, and only 9.6% for the 2-beam IMPT plan compared with the 2-beam non-LETd optimized IMPT plan. In case of LET optimization for the brain case, the SPArc plan could effectively increase the average LETd in the CTV and decrease the values in the critical structures while smaller improvement was observed in 3-beam IMPT plans.ConclusionThis work demonstrates the feasibility and significant advantages of using SPArc for LETd-based optimization, which could maximize the LETd distribution wherever is desired inside the target and averts the high LETd away from the adjacent critical organs-at-risk.

scholarly journals PV-0136: Linear energy transfer in normal tissues in spot scanning proton therapy of pro state cancer

2017 ◽  
Vol 123 ◽  
pp. S64-S65
Author(s):  
J. Pedersen ◽  
J. Bb Petersen ◽  
C.H. Stokkevåg ◽  
K.S. Ytre-Hauge ◽  
O. Casares-Magaz ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Proton Therapy ◽  
Linear Energy Transfer ◽  
Normal Tissues ◽  
Spot Scanning

SU-E-T-515: Investigating the Linear Energy Transfer Dependency of Different PRESAGE Formulations in a Proton Beam

2015 ◽  
Vol 42 (6Part20) ◽  
pp. 3453-3453
Author(s):  
M Carroll ◽  
M Alqathami ◽  
A Blencowe ◽  
G Ibbott
Keyword(s):  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer

A Monte Carlo study for the calculation of the average linear energy transfer (LET) distributions for a clinical proton beam line and a radiobiological carbon ion beam line

2014 ◽  
Vol 59 (12) ◽  
pp. 2863-2882 ◽  
Author(s):  
F Romano ◽  
G A P Cirrone ◽  
G Cuttone ◽  
F Di Rosa ◽  
S E Mazzaglia ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Proton Beam ◽  
Linear Energy Transfer ◽  
Ion Beam ◽  
Monte Carlo Study ◽  
Beam Line ◽  
Carbon Ion ◽  
Carbon Ion Beam
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